Formulations containing sphinganine

1. A formulation, comprising:

component A): sphinganine in an amount of at least 0.05% by weight; and

component B): one or more active ingredients selected from the group consisting of: creatine; creatinine; caffeine; carnitine; biotin; arjunolic acid; xymenynic acid; minoxidil; arginine; and derivatives thereof, wherein said derivatives are acids, esters, amides, alcohols, alcoholates, aldehydes, amines, salts, hydrates, glucosides, isomers or enantiomers of said active ingredients;

and wherein sphinganine and said active ingredients are present in amounts such that said formulation is more effective at stimulating the proliferation of follicular dermal papilla cells in vitro, or hair growth in vivo, than the stimulation that can be obtained when either said sphinganine or said active ingredients are present in the absence of the other.

2. The formulation of claim 1 , wherein component B comprises one or more derivatives selected from the group consisting of: creatine hydrates; disodium phosphocreatine; caffeine benzide; caffeine carboxylic acid; caffeine hydrates; carnitine HCl; acetyl carnitine; acetyl carnitine HCl; carnitine fumarate; carnitine hydroxycitrate; carnitine linoleate; carnitine pyroglutamate; carnitine tartrate; palmitoyl carnitine; D/L-carnitine; D/L-carnitine HCl; hexadecanoyl carnitine; levo carnitine; allantoin biotin; biotinoyl hexapeptide-2 amide; biotinoyl pentapeptide-4; biotinoyl tripeptide-1; biotinoyl tripeptide-35; ethyl biotinate; monoethanolamine biotinate biotin ethyl ester; biotinum; acetyl arginine; and arginine HCl.

3. The formulation of claim 1 , wherein component A is present at a concentration of 0.05% by weight to 5.0% by weight.

4. The formulation of claim 1 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

5. The formulation of claim 2 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

6. The formulation of claim 3 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

7. The formulation of claim 2 , wherein component A is present at a concentration of 0.05% by weight to 1.0% by weight.

8. The formulation of claim 7 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

9. The formulation of claim 1 , wherein the weight ratio of component A to component B is 1:1 to 1:2000.

10. The formulation of claim 9 , wherein component B comprises one or more derivatives selected from the group consisting of: creatine hydrates; disodium phosphocreatine; caffeine benzide; caffeine carboxylic acid; caffeine hydrates; carnitine HCl; acetyl carnitine; acetyl carnitine HCl; carnitine fumarate; carnitine hydroxycitrate; carnitine linoleate; carnitine pyroglutamate; carnitine tartrate; palmitoyl carnitine; D/L-carnitine; D/L-carnitine HCl; hexadecanoyl carnitine; levo carnitine; allantoin biotin; biotinoyl hexapeptide-2 amide; biotinoyl pentapeptide-4; biotinoyl tripeptide-1; biotinoyl tripeptide-35; ethyl biotinate; monoethanolamine biotinate biotin ethyl ester; biotinum; acetyl arginine; and arginine HCl.

11. The formulation of claim 9 , wherein component A is present at a concentration of 0.05% by weight to 5.0% by weight.

12. The formulation of claim 9 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

13. The formulation of claim 10 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

14. The formulation of claim 11 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.

15. The formulation of claim 10 , wherein component A is present at a concentration of 0.05% by weight to 1.0% by weight.

16. The formulation of claim 15 , wherein component B is present at a concentration of 0.01% by weight to 20.0% by weight.