METHODS FOR USING NITRIC OXIDE IN A PLASMA STATE TO TREAT MEDICAL CONDITIONS AND DISEASES
Methods for administering nitric oxide (NO) in a plasma state to a treatment site are disclosed. A discrete stream of matter is placed in a plasma state, in which the stream has, as part of its content, a desired concentration of NO. The discrete stream of matter is directed at a site of action to achieve a therapeutic result.
1 . A method for administering nitric oxide in a plasma state to an organism, the method comprising:
creating a discrete stream of matter that has been put into a state of plasma, in which the stream has, as part of its content, nitric oxide (NO) in a concentration from about 200 ppm to 1000 ppm; and
directing the discrete stream of matter at a site of action to obtain a therapeutic result by at least one of stimulating sub-dermal production of NO, mobilization of NO in a plasma state across and through the dermis, and the direct effect of NO in a plasma state on pathogens.
2 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action comprises positioning a device used to create the discrete stream of matter from 1 to 25 centimeters from the device to the site.
3 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action comprises directing the discrete stream of matter for 5 to 45 seconds for each square centimeter of site area.
4 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action comprises inhalation of the discrete stream of matter for a predetermined number of breaths.
5 . The method of claim 1 , wherein the discrete stream of matter is directed to the site over a plurality of discrete application procedures, wherein the plurality of discrete application procedures is from 1 to 24 discrete applications.
6 . The method of claim 1 , further comprising directing the discrete stream of matter to the site over multiple discrete time periods, the time periods separated by from 3 to 168 hours.
7 . The method of claim 1 , wherein the temperature of the stream at contact with the site is from 10 to 60 degrees C.
8 . The method of claim 1 , wherein the velocity of the stream at contact with the site is from 0.5 to 200 meters per second.
9 . The method of claim 1 , wherein the stream of nitric oxide plasma is creating using an electric arc discharge device.
10 . The method of claim 1 , wherein the stream of nitric oxide plasma is creating using a microwave discharge device.
11 . The method of claim 1 , wherein the stream of nitric oxide plasma is creating using a gliding arc discharge device.
12 . The method of claim 1 , wherein the therapeutic result is selected from the list consisting of facilitating hair-growth, reducing wrinkles, facilitating vasodilation, alleviating pain associated with osteoarthritis and Rheumatoid Arthritis, combating Gram Positive microorganisms, combating Gram Negative microorganisms, combating fungi and viruses, combating asthma, combating respiratory infections, combating pre insult keloidosis, and combating post insult keloidosis.
13 . The method of claim 1 , wherein the therapeutic result is selected from the list consisting of treating osteoporosis, collagen formation, stem cell signaling, satellite cell differentiation, wound healing, wound management, acne, nerve regeneration, inhibiting cancer cell proliferation, promoting apoptosis, stimulating endogenous nitric oxide production, and stimulating iNOS pathways.
14 . The method of claim 1 , wherein the therapeutic result is selected from the list consisting of maintaining homeostasis in the cardiovascular and respiratory systems, causing vasodilation, easing blood pressure, cleaning the blood, reversing atherosclerosis, preventing cardiovascular diseases, slowing down atherosclerotic plaque deposition on vascular walls, suppressing bacterial infections, suppressing viruses and parasitic attacks, deterring cancer cell growth, reducing pain associated with joint swelling in arthritis, decreasing the risk of cancer, diabetes, myocardial infarction and stroke.
15 . The method of claim 1 , wherein the therapeutic result is selected from the list consisting of facilitating hair-growth, reducing wrinkles, facilitating vasodilation, alleviating pain associated with osteoarthritis and Rheumatoid Arthritis, combating Gram Positive microorganisms, combating Gram Negative microorganisms, combating fungi and viruses.
16 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
5
45
Number of treatments
1
24
Length of time between treatments (hours)
3
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
17 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
10
90
Number of treatments
1
24
Length of time between treatments (hours)
3
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
18 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Maximum
Parameter
Minimum Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
1
45
Number of treatments
1
200
Length of time between treatments (hours)
3
168
Temperature of plasma stream at contact
10
60
with Site ° C.
Velocity of Plasma Stream at contact with
0.5
200
Site (m/sec)
19 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
5
90
Number of treatments
1
200
Length of time between treatments (hours)
3
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
20 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
5
45
Number of treatments
1
24
Length of time between treatments (hours)
3
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
21 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
10
30
Time of Application (sec/cm 2 )
10
90
Number of treatments
1
200
Length of time between treatments (hours)
1
168
Temperature of plasma stream at contact with
10
50
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
22 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
5
25
Time of Application (sec/cm 2 )
10
45
Number of treatments
3
40
Length of time between treatments (hours)
12
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
23 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
15
120
Number of treatments
3
50
Length of time between treatments (hours)
12
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
24 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
3
25
Time of Application (sec/cm 2 )
30
90
Number of treatments
3
40
Length of time between treatments (hours)
12
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
25 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
1
25
Time of Application (sec/cm 2 )
20
120
Number of treatments
3
60
Length of time between treatments (hours)
12
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
26 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
6
25
Time of Application (sec/cm 2 )
10
30
Number of treatments
10
100
Length of time between treatments (hours)
12
72
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
27 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
6
25
Time of Application (sec/cm 2 )
5
30
Number of treatments
4
24
Length of time between treatments (hours)
12
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
28 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
6
25
Time of Application (sec/cm 2 )
10
30
Number of treatments
1
12
Length of time between treatments (hours)
3
72
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
29 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
8.5
35
Application (inhalation) breaths
2
45
Number of treatments
1
42
Length of time between treatments (hours)
3
48
Temperature of plasma stream at contact with
10
40
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
30 . The method of claim 1 , wherein directing the discrete stream of matter at a site of action is undertaken according to the following criteria:
Minimum
Maximum
Parameter
Value
Value
Distance from exit to site (cm)
6
25
Time of Application (sec/cm 2 )
5
30
Number of treatments
1
20
Length of time between treatments (hours)
3
168
Temperature of plasma stream at contact with
10
60
Site ° C.
Velocity of Plasma Stream at contact with Site
0.5
200
(m/sec)
31 . The method of claim 1 , wherein the discrete stream of matter comprises:
Minimum
Maximum
Parameter
Value
Value
Nitric Oxide (NO)
200
ppm
1000
ppm
NO 2
0
ppm
25
ppm
N 2
75
vol %
78
vol %
O 2
18
vol %
21
vol %
O 3
0
ppm
0.1
ppm
H 2 O 2
0
ppm
1500
ppm
H 2 O
0
ppm
20000
ppm
Ar
1 * 10{circumflex over ( )}4
ppm
9.1 * 10{circumflex over ( )}5
ppm
He
5.2
ppm
9.1 * 10{circumflex over ( )}5
ppm
CO
0
ppm
50
ppm
CO 2
300
ppm
500
ppm
H2
0
ppm
10000
ppm
32 . The method of claim 1 , wherein the discrete stream of matter comprises:
Minimum
Maximum
Parameter
Value
Value
Nitric Oxide (NO)
50
ppm
800
ppm
NO 2
0
ppm
25
ppm
N 2
75
vol %
95
vol %
O 2
3
vol %
21
vol %
O 3
0
ppm
0.1
ppm
H 2 O 2
0
ppm
1500
ppm
H 2 O
0
ppm
20000
ppm
Ar
1 * 10{circumflex over ( )}4
ppm
9.1 * 10{circumflex over ( )}5
ppm
He
5.2
ppm
9.1 * 10{circumflex over ( )}5
ppm
CO
0
ppm
50
ppm
CO 2
0
ppm
500
ppm
H2
0
ppm
10000
ppm