IP Library › Granted Patent US 10,233,417
Granted Patent B2
US 10,233,417 · App. 14/917,726 · Granted Mar 19, 2019

Container with flexible walls

Inventors: Heinz-Ruediger Keitel (Melsungen, DE); Bernward Husemann (Goettingen, DE); Wolfgang Kahlert (Koerle, DE)
Assignee: Sartorius Stedim Biotech GmbH
C12M23/26C12M23/14C12M23/28C12M23/34C12M41/02C12M41/44C12M41/48
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Quick Facts
Patent No.
US 10,233,417
App. No.
14/917,726
Granted
Mar 19, 2019
Kind
B2
Abstract

A container ( 2 ) has flexible walls surrounding a container interior ( 6 ). At least one electrical sensor ( 3, 3′, 3″, 3′″, 3 ″″) projects into the container interior ( 6 ) and has at least first and second electrically conductive plates ( 8, 8′, 9, 9′, 9 ′″) for determining the conductivity or impedance of a medium that surrounds the plates ( 8, 8′, 9, 9′, 9 ′″). The plates ( 8, 8′, 9, 9′, 9 ′″) are connected via connecting lines ( 10, 11 ) to a control and regulating unit ( 4 ) outside the container interior ( 6 ). At least the first plate ( 8, 8 ′) is on a closed free end of a sheathing ( 5, 5′, 5 ″″) and has a contact area exposed to the surrounding medium. The sheathing ( 5, 5′, 5″″, 17, 17 ″″) is a flexible hose ( 7 ) or bellows ( 19, 19 ″″) through which the electrical connecting line ( 10, 11 ) of the plate ( 8, 8′, 9, 9′, 9 ′″) is routed.

Claims (14)

1. A container ( 2 ) with flexible walls defining a container interior ( 6 ) and at least one wall aperture ( 20 ) formed in at least a first of the flexible walls, a first sheathing ( 5 , 5 ′, 5 ″) having a first end connected to the first flexible wall so that an interior of the first sheathing ( 5 , 5 ′, 5 ″″) communicates with the at least one wall aperture ( 20 ), the first sheathing ( 5 , 5 ′, 5 ″″) having a closed free second end in the container interior ( 6 ), at least one electrical sensor ( 3 , 3 ′, 3 ″, 3 ′″, 3 ″″) having at least first and second electrically conductive plates ( 8 , 8 ′, 9 , 9 ′, 9 ′″), each of which has a contact surface disposed to be exposed to a medium in the container ( 2 ), the electrically conductive plates ( 8 , 8 ′, 9 , 9 ′, 9 ′″) being connected via connecting lines ( 10 , 11 ) to an external area that is arranged outside the container interior ( 6 ), at least the first plate ( 8 , 8 ′) being arranged on the closed, free second end of a first sheathing ( 5 , 5 ′, 5 ″″), and the electrical connecting line ( 10 , 11 ) of at least the first plate ( 8 , 8 ′) being routed through the first sheathing ( 5 , 5 ′, 5 ″) to the external area, wherein

the first sheathing ( 5 , 5 ′, 5 ″″, 17 , 17 ′″) is a flexible hose ( 7 ) or folding bellows ( 19 , 19 ″″) that is adjustable in length in the container interior ( 6 ), so that at least the first plate ( 8 , 8 ′) is moveable with the closed, free second end of the first sheathing ( 5 , 5 ′, 5 ″″) to plural positions relative to the medium in the container ( 2 ).

2. The container of claim 1 , further comprising a tube ( 21 ) or a positioning rod ( 24 ) that is longitudinally displaceable with respect to the wall aperture ( 20 ), the tube ( 21 ) or the positioning rod ( 24 ) being arranged within the first sheathing ( 5 ″″, 17 ′″), which is designed as the bellows ( 19 , 19 ″″), an end of the tube or the rod facing toward the plate ( 8 ′, 9 ′″) being connected to the free second end of the bellows ( 19 , 19 ″″).

3. The container of claim 2 , wherein the end of the longitudinally displaceable tube ( 21 ) that faces away from the plate ( 9 ′″) projects outside of the container interior ( 6 ).

4. The container of claim 2 , wherein the wall aperture ( 20 ) has an adapter piece ( 22 ) in which the longitudinally displaceable tube ( 21 ) is arranged, the end of the tube facing the container interior ( 6 ) being connected to the bellows ( 19 ).

5. The container of claim 1 , wherein the free second end of the first sheathing ( 5 ) has a second plate ( 9 ) arranged at a distance from the first plate ( 8 ).

6. The container of claim 1 , further comprising a second sheathing ( 17 , 17 ′″) with a closed free end, the second plate ( 9 ′, 9 ′″) being arranged on the closed, free end of the second sheathing ( 17 , 17 ′″).

7. The container of claim 1 , wherein the second plate ( 9 ′) is arranged directly on an inner side of the flexible wall ( 18 ) facing the container interior ( 6 ) and the exposed contact surface of the second plate ( 9 ′) facing away from the wall ( 18 ).

8. The container of claim 1 , wherein the contact surfaces of the plates ( 8 , 8 ′, 9 , 9 ′, 9 ′″) are arranged above an intended fluid level.

9. The container of claim 1 , wherein the sensor ( 3 , 3 ′, 3 ″, 3 ′″, 3 ″″) formed by the at least first and second plates ( 8 , 8 ′, 9 , 9 ′, 9 ′″) is designed for detection of fluid ( 13 ) and/or foam ( 12 ).

10. The container of claim 9 , further comprising a pump or a valve ( 14 ) arranged in an inlet line ( 15 ) running between the flexible container ( 2 ) and a reservoir ( 16 ) containing an antifoam agent.

11. The container of claim 1 , wherein the container ( 2 ) with the sensor ( 3 , 3 ′, 3 ″, 3 ′″, 3 ″″) is a single-use container.

12. The container of claim 1 , wherein the container ( 2 ) with the sensor ( 3 , 3 ′, 3 ″, 3 ′″, 3 ″″) is designed so as to be capable of being folded up.

13. The container of claim 1 , wherein the container ( 2 ) is a bioreactor ( 1 ).

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 18, 2016
From: KAHLERT, WOLFGANG
To: SARTORIUS STEDIM BIOTECH GMBH
Reel/Frame 038033/0037 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 9, 2016
From: HUSEMANN, BERNWARD
To: SARTORIUS STEDIM BIOTECH GMBH
Reel/Frame 037933/0270 →
Priority Claims (1)
DE 10 2013 109 820 · Sep 9, 2013 · national
Continuity (1)
Related Publication 20160215248A1 · Jul 28, 2016
Cited By (2)
US 12,422,294 US 12,624,326