IP Library Granted Patent US 9,642,876
Granted Patent B2
US 9,642,876 · App. 14/924,361 · Granted May 9, 2017

Method of preventing or treating sinusitis with oxidative reductive potential water solution

Inventor: Hojabr Alimi (Santa Rosa, CA)
Assignee: SONOMA PHARMACEUTICALS, INC.
A61K33/20A01N59/00A61K9/007A61K9/0014A61K9/0019A61K33/00A61K45/06A61K47/32A61L2/0088A61L2/186C02F1/4618C02F1/4672A61L2/035A61L2/22A61L2202/11A61L2202/122A61L2202/17A61L2202/24C02F1/4674C02F1/722C02F1/76C02F2001/46195C02F2103/026C02F2201/4618C02F2201/46115C02F2209/04C02F2209/06C02F2209/40C02F2303/04
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Quick Facts
Patent No.
US 9,642,876
App. No.
14/924,361
Granted
May 9, 2017
Kind
B2
Abstract

Provided is a method for preventing or treating sinusitis by administering a therapeutically effective amount of an oxidative reduction potential (ORP) water solution that is stable for at least about twenty-four hours. The ORP water solution administered in accordance with the invention can be combined with one or more suitable carriers. The ORP water solution can be administered alone or, e.g., in combination with one or more additional therapeutic agents.

Claims (19)

1. A method of treating sinusitis in a patient, the method comprising administering to the patient a therapeutically effective amount of an oxidative reductive potential water solution, wherein the solution is stable for at least about two months and the solution has a pH of from about 6.4 to about 7.8, wherein the sinusitis results from an infection by one or more bacteria.

2. The method of claim 1 , comprising administering the oxidative reductive potential water solution to the upper respiratory airway.

3. The method of claim 1 , comprising delivering the oxidative reductive potential water solution in the form of a liquid.

4. The method of claim 1 , wherein the sinusitis is acute sinusitis.

5. The method of claim 1 , wherein the sinusitis further results from a fungal infection.

6. The method of claim 5 , wherein the fungal infection is by one or more fungi selected from the group of zygomycetes, aspergillus , and candida.

7. The method of claim 1 , wherein the sinusitis further results from an allergic reaction.

8. The method of claim 7 , wherein the allergic reaction is caused by dust, mold, pollen, or a combination thereof.

9. The method of claim 1 , wherein the pH of the oxidative reductive potential water solution is from about 7.4 to about 7.6.

10. The method of claim 1 , wherein the oxidative reductive potential water solution comprises from about 10% by volume to about 50% by volume of cathode water and from about 50% by volume to about 90% by volume of anode water.

11. The method of claim 1 , wherein the oxidative reductive potential water solution comprises a free chlorine species comprising hypochlorous acid, a hypochlorite ion, sodium hypochlorite, chlorite ion, or a combination or two or more of any of these.

12. The method of claim 1 , wherein the oxidative reductive potential water solution comprises from about 15 ppm to about 35 ppm hypochlorous acid.

13. The method of claim 1 , wherein the oxidative reductive potential water solution comprises from about 25 ppm to about 50 ppm sodium hypochlorite.

14. The method of claim 1 , wherein the oxidative reductive potential water solution comprises from about 15 ppm to about 35 ppm hypochlorous acid, and from about 25 ppm to about 50 ppm sodium hypochlorite.

15. The method of claim 1 , further comprising administering an additional therapeutic agent comprising an antihistamine, decongestant, anti-infective agent, anti-inflammatory agent, or a combination of two or more of any of these.

16. The method of claim 1 , wherein the sinusitis is chronic sinusitis.

17. The method of claim 1 , comprising delivering the oxidative reductive potential water solution in the form of a spray or aerosol.

18. The method of claim 1 , comprising delivering the oxidative reductive potential water solution in the form of a mist or steam.

19. The method of claim 1 , wherein the oxidative reductive potential water solution comprises from about 20% by volume to about 40% by volume of cathode water.

Assignments (2)
CHANGE OF NAME Recorded Jan 5, 2017
From: OCULUS INNOVATIVE SCIENCES, INC.
To: SONOMA PHARMACEUTICALS, INC.
Reel/Frame 041257/0375 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2015
From: ALIMI, HOJABR
To: OCULUS INNOVATIVE SCIENCES, INC.
Reel/Frame 036938/0124 →
Continuity (4)
Continuation 10916566 · Aug 11, 2004
Continuation In Part 10862092 · Jun 4, 2004
Provisional Application 60533583 · Dec 30, 2003
Related Publication 20160045547A1 · Feb 18, 2016