Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.
1. A conformal sensor tape for monitoring vital signs, the tape comprising:
a conformal substrate;
an integrated circuit mounted on the conformal substrate;
an inductive transmitter coil mounted on the conformal substrate and coupled to the integrated circuit;
a positive electrode coupled to the integrated circuit; and
a negative electrode coupled to the integrated circuit;
wherein electrical signals received by the positive electrode and the negative electrode are transferred to the integrated circuit, and the integrated circuit induces an RF signal in the inductive transmitter coil.
2. The conformal sensor tape of claim 1 , further comprising an amplifier connecting at least one of the positive electrode and the negative electrode to the integrated circuit.
3. The conformal sensor tape of claim 1 , further comprising a ground electrode coupled to the integrated circuit.
4. The conformal sensor tape of claim 1 , wherein the conformal substrate has a perimeter portion and a central portion, and the positive electrode and the negative electrode are located in the central portion of the conformal substrate, and wherein the inductive transmitter coil extends along the perimeter portion around the positive electrode and the negative electrode.
5. The conformal sensor tape of claim 1 , wherein the positive electrode and the negative electrode are ECG electrodes.
6. The conformal sensor tape of claim 1 , wherein the tape has a thickness of 300 to 500 μm.
7. The conformal sensor tape of claim 1 , further comprising one or more passive filters coupled to the integrated circuit and configured to optimize signal to noise ratio.
8. The conformal sensor tape of claim 1 , further comprising a capacitor coupled to at least one of the inductive transmitter coil and the integrated circuit.
9. The conformal sensor tape of claim 1 , wherein the conformal substrate is formed of (poly)dimethylsiloxane (PDMS).
10. The conformal sensor tape of claim 1 , wherein the vital signs relate to one or more of surface topology, temperature, pressure, electrical conductivity, pH, chemical, and enzymatic activity of a user upon which the tape is placed.
11. The conformal sensor tape of claim 1 , wherein the inductive transmitter coil, the positive electrode, and the negative electrode are coupled to the integrated circuit via stretchable electrical interconnects.
12. The conformal sensor tape of claim 1 , wherein the integrated circuit is flexible.
13. The conformal sensor tape of claim 1 , wherein the conformal substrate has a perimeter portion, and the inductive transmitter coil extends along at least a portion of the perimeter portion.
14. The conformal sensor tape of claim 13 , wherein the inductive transmitter coil extends along an entirety of the perimeter portion.
15. The conformal sensor tape of claim 1 , further comprising a power source coupled to the integrated circuit.
16. The conformal sensor tape of claim 15 , wherein the power source is a battery.
17. The conformal sensor tape of claim 1 , further comprising an inductive receiver coil coupled to the integrated circuit.
18. The conformal sensor tape of claim 17 , wherein the conformal substrate has a perimeter portion and a central portion, the inductive transmitter coil extends along at least a portion of the perimeter portion, and the inductive receiver coil is located in the central portion.
19. The conformal sensor tape of claim 17 , wherein the inductive receiver coil contains 19.5 turns and has an inductance of 20 μH.
20. The conformal sensor tape of claim 19 , wherein the inductive transmitter coil contains 16 turns and has an inductance of 220 μH.