PHENYL AMINO PYRIMIDINE COMPOUNDS AND USES THEREOF
The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.
1 - 23 . (canceled)
24 . A method of treating a hyperproliferative disorder comprising administering to a patient in need thereof a compound of the formula:
or a pharmaceutically acceptable salt thereof.
25 . The method of claim 24 , wherein the hyperproliferative disorder is cancer.
26 . The method of claim 24 , wherein the hyperproliferative disorder is acute myelogenous leukemia.
27 . The method of claim 24 , wherein the hyperproliferative disorder is acute lymphocytic leukemia.
28 . The method of claim 24 , wherein the hyperproliferative disorder is glioma.