IP Library › Granted Patent US 10,005,840
Granted Patent B2
US 10,005,840 · App. 14/970,578 · Granted Jun 26, 2018

Method for treatment of osteoarthritis with C-Fms antagonists

Inventors: Stefan Steidl (Munich, DE); John Allan Hamilton (Aberfeldie, AU); Andrew David Cook (North Melbourne, AU)
Assignees: MORPHOSYS AG; THE UNIVERSITY OF MELBOURNE
C07K16/2866C07K16/243C07K16/244C07K16/249A61K2039/505C07K2317/76
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Quick Facts
Patent No.
US 10,005,840
App. No.
14/970,578
Granted
Jun 26, 2018
Kind
B2
Abstract

The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA) and/or pain. In accordance with the present invention, an antagonist of c-Fms is effective in the treatment of osteoarthritis and/or pain. An antagonist of M-CSF includes, but is not limited to, an antibody that is specific for M-CSF, IL-34 or c-Fms.

Claims (2)

1. A method for the treatment of osteoarthritis in a subject, comprising administering to the subject an antagonist of c-Fms, wherein said antagonist of c-Fms is an antibody specific for M-CSF.

2. The method of claim 1 wherein said subject is a human.

Assignments (2)
CHANGE OF NAME Recorded May 1, 2025
From: MORPHOSYS AG
To: MORPHOSYS GMBH
Reel/Frame 071149/0626 →
EXCERPT OF COMMERCIAL REGISTER REFLECTING NEW ADDRESS Recorded May 26, 2017
From: MORPHOSYS AG
To: MORPHOSYS AG
Reel/Frame 042587/0014 →
Priority Claims (1)
EP 11174305 · Jul 18, 2011 · regional
Continuity (3)
Division 14126878
Provisional Application 61508717 · Jul 18, 2011
Related Publication 20160185867A1 · Jun 30, 2016