Self-adherent implants and methods of preparation
Implants are described herein which contain an activated adhesive on at least a portion of the surface of the implant. A release sheet may be positioned over at least a portion of the adhesive. Packages which contain the implants and methods of preparing the implants are also described.
1. A dispenser for activating a packaged implant, said dispenser comprising:
a packaged implant including a medical adhesive and a surgical mesh contained within a peelable package having a top layer and a bottom layer, the top layer and bottom layer defining a first cavity containing the medical adhesive, a second cavity containing the surgical mesh, and a rupturable barrier positioned between the first and second cavity,
a compartment containing the packaged implant, the compartment including a dispensing opening and a structure for rupturing the rupturable barrier of the packaged implant.
2. The dispenser of claim 1 wherein the medical adhesive is selected from the group consisting of polyurethanes, isocyanates and combinations thereof.
3. The dispenser of claim 1 wherein the rupturable barrier is formed by a portion of a top layer and a bottom layer of the package.
4. The dispenser of claim 1 wherein the structure for rupturing said rupturable barrier comprises a contoured ridge which reduces the size of the opening and includes a smooth surface to rupture the rupturable barrier without tearing open the package.
5. The dispenser of claim 1 further comprising a second structure for applying the medical adhesive to at least a portion of the mesh.
6. The dispenser of claim 5 wherein the second structure for applying the medical adhesive is selected from the group consisting of wipers, rollers, brushes and combinations thereof.
7. The dispenser of claim 6 wherein the second structure for applying the medical adhesive is a roller.
8. The dispenser of claim 1 wherein the dispensing opening is configured to allow for the passage of the packaged implant out of the compartment after the rupturable barrier has been ruptured and at least some of the medical adhesive in the first cavity moves into the second cavity and in contact with the surgical mesh.
9. The dispenser of claim 1 wherein the top and bottom layers define a sealed perimeter of the peelable package.
10. The dispenser of claim 9 wherein the first and second cavities are defined within the sealed perimeter of the peelable package.