Pupilary screening system and method
A method of screening a pupil of a subject to determine whether the pupil reflex resembles a canonical pupil reflex is disclosed. The method comprises the steps of stimulating the pupil with a stimulus source, such as a pupilometer and determining whether one of various pupillary response conditions is met.
1. A pupilometer, comprising:
a stimulus source;
an imaging system comprising an imaging sensor that detects and monitors a pupillary response following delivery of a stimulus from the stimulus source; and
a microprocessor coupled to the imaging system, wherein the microprocessor is configured to perform the steps of:
(a) processing pupil data comprising pupil diameter measurements as a function of time;
(b) determining time values associated with each of a plurality of pupil diameter values;
(c) determining whether the following conditions are met:
(i) no more than two data points exist representing the same pupil diameter at separate points in time during a period of no more than about four seconds,
(ii) a first phase of the pupilary reflex response exists, wherein said first phase is characterized by a period of non-constriction immediately subsequent to stimulating the pupil, said first phase having a duration of greater than about 100 msec and less than about 1000 msec,
(iii) if two data points exist representing the same pupil diameter at two separate points in time, then the duration of time between said two separate points in time is greater than about 100 msec, and
(iv) during the first phase of the pupilary reflex, the diameter of the pupil does not increase before it decreases; and
(d) providing an output indicating that the pupil reflex does not resemble a canonical reflex if one or more of said conditions is not met.
2. The pupilometer of claim 1 , wherein the microprocessor is further configured to provide an output indicating that the pupil reflex resembles a canonical reflex if all of said conditions are met.
3. The pupilometer of claim 1 , wherein the stimulus source is selected from the group consisting of a noxious stimulus source, and a light stimulus source.
4. The pupilometer of claim 3 , wherein the stimulus source is the light stimulus source.
5. The pupilometer of claim 4 , wherein the light stimulus source comprises at least one light emitting diode.
6. The pupilometer of claim 1 , wherein the microprocessor is an integral component of the pupilometer.
7. The pupilometer of claim 2 , wherein the microprocessor is an integral component of the pupilometer.
8. The pupilometer of claim 1 , wherein the output provided by the microprocessor in step (d) is an output downloaded to a printer.
9. The pupilometer of claim 2 , wherein the output provided by the microprocessor in step (d) is an output downloaded to a printer.
10. The pupilometer of claim 1 , further comprising a viewing port to aid in positioning the pupilometer, and an illumination system that comprises an infrared light source.