Hypertension therapy implant apparatus
An implant unit according to some embodiments may include a flexible carrier, at least one pair of modulation electrodes on the flexible carrier, and at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes. The at least one pair of modulation electrodes and the at least one circuit may be configured for implantation through derma on an underside of a subject's chin and for location proximate to terminal fibers of the medial branch of the subject's hypoglossal nerve, such that an electric field extending from the at least one pair of modulation electrodes can modulate one or more of the terminal fibers of the medial branch of the hypoglossal nerve.
1. A hypertension therapy implant unit, comprising:
a flexible carrier;
at least one pair of modulation electrodes on the flexible carrier; and
at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes, wherein the at least one pair of modulation electrodes and the at least one circuit are configured for subcutaneous, non-intravascular implantation in a subject proximal to a glossopharyngeal nerve,
wherein the implantable circuit and the at least one pair of modulation electrodes are configured to cooperate in order to generate an electric field adapted to cause modulation of at least a portion of the glossopharyngeal nerve,
wherein the implantable circuit includes a non-linear circuit component having non-linear behavior that causes adjustment to the electric field for causing modulation of at least the portion of the glossopharyngeal nerve; and
an internal antenna configured to transmit a signal indicative of the non-linear behavior to an external antenna, the internal antenna being mounted on or integrated with the flexible carrier.
2. The hypertension therapy implant unit of claim 1 , wherein the subcutaneous, non-intravascular implantation includes implantation at a location behind an ear or in a neck of the subject.
3. The hypertension therapy implant unit of claim 1 , wherein the at least one pair of modulation electrodes are configured to be spaced apart from each other along a longitudinal direction of at least the portion of the glossopharyngeal nerve.
4. The hypertension therapy implant unit of claim 1 , wherein the implantable circuit and the at least one pair of modulation electrodes are configured to cooperate to generate the electric field to cause modulation of the glossopharyngeal nerve through intervening tissue.
5. A hypertension therapy implant unit, comprising:
a flexible carrier;
at least one pair of modulation electrodes on the flexible carrier;
an antenna being mounted on or integrated with the flexible carrier;
at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes, wherein the at least one pair of modulation electrodes and the at least one circuit are configured for subcutaneous, non-intravascular implantation in a subject proximal to a glossopharyngeal nerve,
wherein the implantable circuit is configured to electromagnetically couple with the antenna;
wherein the implantable circuit and the at least one pair of modulation electrodes are configured to cooperate to generate an electric field to cause modulation of at least a portion of the glossopharyngeal nerve based on a degree of coupling between the implantable circuit and the antenna;
wherein the implantable circuit includes a non-linear circuit component having non-linear behavior that causes adjustment to the electric field for causing modulation of at least the portion of the glossopharyngeal nerve; and
wherein the antenna is configured to transmit a signal indicative of the non-linear behavior to an external antenna.
6. The hypertension therapy implant unit of claim 5 , wherein the subcutaneous, non-intravascular implantation includes implantation at a location behind an ear or in a neck of the subject.
7. The hypertension therapy implant unit of claim 5 , wherein the at least one pair of modulation electrodes are configured to be spaced apart from each other along a longitudinal direction of at least the portion of the glossopharyngeal nerve.
8. The hypertension therapy implant unit of claim 5 , wherein the implantable circuit and the at least one pair of modulation electrodes are configured to cooperate to generate the electric field to cause modulation of the glossopharyngeal nerve through intervening tissue.