IP Library Granted Patent US 9,549,911
Granted Patent B2
US 9,549,911 · App. 15/010,011 · Granted Jan 24, 2017

Ginger metabolites and uses thereof

Inventors: Shengmin Sang (Concord, NC); Huadong Chen (Kannapolis, NC); Yingdong Zhu (Kannapolis, NC)
Assignee: North Carolina A&T State University
A61K31/198A61K36/9068C07D487/04C07D519/00
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Quick Facts
Patent No.
US 9,549,911
App. No.
15/010,011
Granted
Jan 24, 2017
Kind
B2
Abstract

The present application generally relates to the use of metabolites of ginger and analogs thereof for the treatment and prevention of diseases, including but not limited to, cancer.

Claims (14)

1. A method of treating lung cancer in a subject in need thereof, comprising the steps of: administering to said subject a therapeutically effective amount of a compound having the formula:

wherein n is selected from the group consisting of 2, 4, 6 and combinations thereof.

2. The method of claim 1 wherein the step of administering a compound having said formula includes the step of including a pharmaceutically acceptable salt or hydrate of said formula.

3. The method of claim 1 , wherein said compound is in an isolated or purified form.

4. A method of treating colon cancer in a subject in need thereof, comprising the steps of: administering to said subject a therapeutically effective amount of a compound having the formula:

wherein n is selected from the group consisting of 2, 4, 6 and combinations thereof.

5. The method of claim 4 wherein the step of administering a compound having said formula includes the step of including a pharmaceutically acceptable salt or hydrate of said formula.

6. The method of claim 4 , wherein said compound is in an isolated or purified form.

7. The method of claim 1 wherein n is 2.

8. The method of claim 1 wherein n is 4.

9. The method of claim 1 , wherein n is 6.

10. The method of claim 4 , wherein n is 2.

11. The method of claim 4 , wherein n is 4.

12. The method of claim 4 , wherein n is 6.

Assignments (1)
CONFIRMATORY LICENSE Recorded Aug 4, 2016
From: NORTH CAROLINA AGRI & TECH ST UNIV
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039337/0545 →
Continuity (4)
Division 14134504 · Dec 19, 2013
Provisional Application 61790281 · Mar 15, 2013
Provisional Application 61739169 · Dec 19, 2012
Related Publication 20160235697A1 · Aug 18, 2016