IP Library Granted Patent US 9,471,870
Granted Patent B2
US 9,471,870 · App. 15/014,328 · Granted Oct 18, 2016

Brain-machine interface utilizing interventions to emphasize aspects of neural variance and decode speed and angle using a kinematics feedback filter that applies a covariance matrix

Inventors: Jonathan C. Kao (Stanford, CA); Chethan Pandarinath (E Palo Alto, CA); Paul Nuyujukian (Stanford, CA); Krishna V. Shenoy (Palo Alto, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
G06N3/08A61B5/04001A61F2/72G06F3/015Y10S128/905
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Quick Facts
Patent No.
US 9,471,870
App. No.
15/014,328
Granted
Oct 18, 2016
Kind
B2
Abstract

A brain machine interface (BMI) for restoring performance of poorly performing decoders is provided. The BMI has a decoder for decoding neural signals for controlling the brain machine interface. The decoder separates in part neural signals associated with a direction of movement and neural signals associated with a speed of movement of the brain machine interface. The decoder assigns relatively greater weight to the neural signals associated with a direction of movement.

Claims (7)

1. An artificial controller of a prosthetic device, comprising:

(a) a brain machine interface having an algorithm executable by a computer, wherein the brain machine interface comprises a mapping from neural signals to corresponding intention estimating kinematics of a limb trajectory, wherein the intention estimating kinematics comprises speeds and angles;

b) the brain machine interface controlling the prosthetic device using recorded neural signals as input to the brain machine interface and the mapping of the brain machine interface determining the intention estimating kinematics to control the prosthetic device, wherein the controller results in an executed movement of the prosthetic device;

(c) a modified brain machine interface having an algorithm executable by the computer for modifying during the control of the prosthetic device, at discrete time intervals over the course of the executed movement of the prosthetic device, the angles in the brain machine interface, wherein each of the modifications of the angles comprises changes in the direction of the angles towards an end target of the executed movement of the prosthetic device;

(d) the modified brain machine interface controlling the prosthetic device; and

(e) a kinematics feedback filter executable by the computer in both the brain machine interface and the modified brain machine interface, wherein the kinematics feedback filter applies a covariance matrix of an a posteriori estimate of the intention estimating kinematics at each time step of the discrete time intervals, whereby the kinematics are modeled as feedback from the interfaces to a user of the prosthetic device.

2. The artificial controller as set forth in claim 1 , further comprising an algorithm for projecting the neural signals into a space of lower dimensionality compared to the dimensionality of the neural signals, and re-weighting the contribution of the dimensions of the lower dimensional space to the estimated kinematics.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 26, 2016
From: KAO, JONATHAN C.; PANDARINATH, CHETHAN; NUYUJUKIAN, PAUL; SHENOY, KRISHNA V.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 039257/0548 →
CONFIRMATORY LICENSE Recorded Jul 11, 2016
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 039298/0850 →
Continuity (5)
Continuation 14309502 · Jun 19, 2014
Continuation In Part 12932070 · Feb 17, 2011
Provisional Application 61338460 · Feb 18, 2010
Provisional Application 61837014 · Jun 19, 2013
Related Publication 20160224891A1 · Aug 4, 2016