IP Library Granted Patent US 9,605,053
Granted Patent B2
US 9,605,053 · App. 15/017,246 · Granted Mar 28, 2017

Influenza virus-neutralizing antibody and screening method therefor

Inventors: Yoshikazu Kurosawa (Aichi, JP); Yoshitaka Iba (Aichi, JP); Nobuko Ohshima (Aichi, JP); Yoshinobu Okuno (Osaka, JP)
Assignees: Fujita Health University; The Research Foundation for Microbial Diseases of Osaka University
C07K16/1018A61K2039/505C07K2317/21C07K2317/33C07K2317/34C07K2317/52C07K2317/55C07K2317/76C07K2319/00
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,605,053
App. No.
15/017,246
Granted
Mar 28, 2017
Kind
B2
Abstract

Provided is an anti-influenza virus antibody that exhibits neutralizing activity beyond the barrier of the two groups of influenza viruses categorized according to the conservativeness of hemagglutinin amino acids, a method of producing the same, and a test method for determining whether the subject carries the neutralizing antibody.

Claims (2)

1. A method of passive immunotherapy for influenza comprising administering an effective amount of an antibody to a mammalian or avian subject that has been infected, or can get infected, with influenza virus, wherein the antibody is an isolated antibody comprising a heavy chain variable region comprising SEQ ID NO:15 and a light chain variable region comprising SEQ ID NO:26, whereby the antibody binds influenza virus HA.

2. The method according to claim 1 , wherein the subject receiving the administration is a human.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 15, 2017
From: KUROSAWA, YOSHIKAZU; IBA, YOSHITAKA; OHSHIMA, NOBUKO
To: FUJITA HEALTH UNIVERSITY
Reel/Frame 041261/0522 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 15, 2017
From: OKUNO, YOSHINOBU
To: THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIVERSITY
Reel/Frame 041261/0539 →
Continuity (4)
Division 13198147 · Aug 4, 2011
Provisional Application 61452785 · Mar 15, 2011
Provisional Application 61380051 · Sep 3, 2010
Related Publication 20160152692A1 · Jun 2, 2016