Fish vaccine
The present document discloses a new species of Bizionia , herein denoted Bizionia piscinecroseptica and a reference strain of this bacterium denoted Bizionia sp. 130524K2F7 which has been deposited at the National Collection of Industrial and Marine Bacteria and has been assigned accession number NCIMB 42183. Further disclosed is the medical use of bacteria of the genus Bizionia for vaccinating fish against a new disease identified and herein denoted bizioniosis.
1. A composition comprising Bizionia sp., wherein said Bizionia sp. is Bizionia piscinecroseptica that is inactivated by formalin.
2. The composition of claim 1 , wherein said Bizionia piscinecroseptica is Bizionia piscinecroseptica 130524K2F7 deposited at National Collection of Industrial, Food and Marine Bacteria under the accession number NCIMB 42183.
3. The composition of claim 1 , wherein said composition further comprises a pharmaceutically acceptable excipient and/or adjuvant.
4. The composition of claim 1 , wherein said composition further comprises additional bacteria of other genera and/or species and/or strains and/or an antigen of said bacteria.
5. The composition of claim 4 , wherein said additional bacteria are inactivated bacteria selected from the group consisting of Moritella viscosa, Aliivibrio wodanis, Tenacibaculum sp., Tenacibaculum maritimum, Vibrio sp., Photobacter sp., Aeromonas salmonicida subspecies, salmonicida, Aliivibrio logei, Aliivibrio salmonicida, Flavobacterium, Flavobacterium psychrophilum, Flavobacterium columnare, Aliivibrio friggiae and/or Vibrio anguillarum.
6. The composition of claim 1 , wherein said composition further comprises Aliivibrio friggiae and/or an antigen(s) thereof, wherein the Aliivibrio friggiae are inactivated.
7. The composition of claim 1 , wherein said composition further comprises Aliivibrio wodanis and/or an antigen(s) thereof, wherein the Aliivibrio wodanis are inactivated.
8. The composition of claim 1 , wherein said composition further comprises Aliivibrio wodanis and/or an antigen(s) thereof, and Allivibrio friggiae and/or an antigen(s) thereof, wherein the Aliivibrio friggiae are inactivated.
9. The composition of claim 1 , wherein said composition further comprises Moritella viscosa that are inactivated.
10. A method of immunizing fish against bizioniosis comprising the administration of a pharmaceutically effective amount of a composition comprising inactivated Bizionia piscinecroseptica 130524K2F7 inactivated by heat or formalin to a fish in need thereof.
11. The method according to claim 10 , wherein said administration is performed by intraperitoneal injection, bath vaccination and/or by oral vaccination.