IP Library › Granted Patent US 12,342,808
Granted Patent B2
US 12,342,808 · App. 15/037,513 · Granted Jul 1, 2025

Compositions, devices and methods for control of pests using vapor activity

Inventors: Karan Manhas (Vancouver, CA); Annett Rozek (Port Moody, CA); Nathan Woodbury (Burnaby, CA); Shannon Lentz (Vancouver, CA); Robert James Etsu Takeuchi (Vancouver, CA); Sasha Ozeroff (Vancouver, CA)
Assignee: 0903608 B.C. Ltd.
A01M13/003A01M1/2022A01M1/2027A01M1/2033A01M1/2044A01M1/2055A01M1/2061A01M1/2077A01M17/008A01N25/18A61K31/12A01M2200/011
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Quick Facts
Patent No.
US 12,342,808
App. No.
15/037,513
Granted
Jul 1, 2025
Kind
B2
Abstract

Devices and methods for the control of pests using the vapors of a pesticidal composition. Compostions, devices and methods for the selective control of pests while not harming one or more beneficial insects are also disclosed. In some embodiments, the pests are bed bugs, fleas, lice, ticks, or the like. In some embodiments, the pests are varroa mites and the beneficial insects are honey bees.

Claims (47)

1. A method of killing a pest, the method comprising:

providing a treatment enclosure containing pests or their eggs, or an article infested with pests or their eggs, the treatment enclosure having a volume of between 70 L and 1200 L;

providing a substrate impregnated with a pesticidal composition; and

passively releasing pesticidal vapors of the pesticidal composition from the substrate within the treatment enclosure for a treatment period, wherein the pesticidal composition comprises neem oil;

wherein the concentration of neem oil in the pesticidal composition comprises in the range of about 0.00055% to 0.013% by volume per volume of the treatment enclosure.

2. A method as defined in claim 1 , wherein:

the pesticidal vapors are released within the treatment enclosure for the treatment period so that a void space of the treatment enclosure begins to saturate within 4 hours and reaches saturation within 24 hours as measured by gas chromatography using a diluent as a marker, wherein the diluent optionally comprises isopropyl alcohol.

3. A method as defined in claim 1 , wherein the treatment enclosure is airtight.

4. A method as defined in claim 1 , wherein the treatment enclosure is at least partially permeable to pesticidal vapors.

5. A method as defined in claim 4 , wherein the pests comprise varroa mites and the treatment enclosure comprises a bee hive, and wherein the concentration of the neem oil in the composition comprises in the range of about 0.00055% to 0.00825% by volume per volume of the bee hive, and the concentration of acetophenone in the composition comprises in the range of about 0.001825% to 0.0275% by volume per volume of the bee hive.

6. A method as defined in claim 1 , wherein:

the treatment enclosure has a volume of between 70 L and 200 L and the substrate comprises between 10 mL and 200 mL of the pesticidal composition; and

wherein the pests comprise terrestrial arthropods.

7. A method as defined in claim 6 , wherein the pesticidal composition comprises acetophenone, and the concentration of acetophenone is in the range of about 0.001825% to 0.0365% by volume per volume of treatment enclosure in which it is applied.

8. A method as defined in claim 1 , wherein the composition comprises a diluent, and wherein a peak area of the diluent as measured by gas chromatography reaches at least 750 within 24 hours.

9. A method as defined in claim 8 , wherein the diluent comprises isopropyl alcohol.

10. A method as defined in claim 1 , wherein the pesticidal vapors of the pesticidal composition are released from the substrate so that a void space of the treatment enclosure begins to saturate within 4 hours and reaches saturation within 24 hours.

11. A method as defined in claim 1 for controlling eggs of a pest, wherein the step of providing a treatment enclosure containing pests or their eggs, or an article infested with pests or their eggs comprises providing a treatment enclosure containing the eggs of the pest or an article infested with the eggs of the pest; and wherein the pest comprises a terrestrial arthropod.

12. A method as defined in claim 11 wherein the pesticidal composition comprises a diluent, and wherein a peak area of the diluent as measured by gas chromatography is at least 450 after 5 days.

13. A method as defined in claim 12 , wherein the diluent comprises isopropyl alcohol.

14. A method as defined in claim 1 , wherein the treatment enclosure comprises a volume of between 70 L and 200 L and the substrate comprises between 10 mL and 200 mL of pesticidal composition.

15. A method as defined in claim 1 , wherein the substrate comprises a volume of the pesticidal composition in a range of 10 mL to 100 mL of the pesticidal composition per 100 L volume of the treatment enclosure.

16. A method as defined in claim 1 , wherein the step of providing a substrate impregnated with a pesticidal composition comprises providing the substrate within a housing, the housing comprising a window or series of apertures for releasing pesticidal vapors from the substrate and a peel strip or resealable rigid opening that initially sealingly covers the window or series of apertures, and further comprises opening the peel strip or resealable rigid opening.

17. A method as defined in claim 1 , wherein the treatment enclosure comprises a structure for fully or partially sealing the treatment enclosure, the structure comprising a flexible outer layer that is impermeable or substantially impermeable to pesticidal vapors.

18. A method as defined in claim 17 , further comprising killing the pest inside the treatment enclosure.

19. A method of killing a pest, the method comprising:

providing a treatment enclosure containing pests or their eggs, or an article infested with pests or their eggs; and

releasing pesticidal vapors within the treatment enclosure for a treatment period, the pesticidal vapors being released from a composition comprising neem oil wherein:

the treatment enclosure has a volume of between 70 L and 1200 L; and

the step of releasing pesticidal vapors within the treatment enclosure comprises:

providing a substrate impregnated with a pesticidal composition; and

passively releasing pesticidal vapors of the pesticidal composition from the substrate within the treatment enclosure for a treatment period, wherein the pesticidal composition is applied at a concentration in the range of 0.01% to 0.2% vol/vol relative to the volume of the treatment enclosure in which it is applied;

wherein the pests comprise terrestrial arthropods.

20. A method as defined in claim 19 , wherein the pesticidal composition comprises acetophenone at a concentration in the range of about 0.001825% to 0.0365% by volume per volume of treatment enclosure in which it is applied.

21. A method as defined in claim 20 , wherein the concentration of the neem oil is in the range of about 0.00055% to 0.013% by volume per volume of treatment enclosure in which it is applied.

22. A method as defined in claim 19 for controlling eggs of a pest, wherein the step of providing a treatment enclosure containing pests or their eggs or an article infested with pests or their eggs comprises providing the treatment enclosure containing the eggs of the pest or an article infested with the eggs of the pest.

23. A method as defined in claim 22 , wherein the pesticidal composition comprises acetophenone at a concentration in the range of about 0.001825% to 0.0365% by volume per volume of treatment enclosure in which it is applied.

24. A method as defined in claim 23 , wherein the concentration of the neem oil is in the range of about 0.00055% to 0.011% by volume per volume of treatment enclosure in which it is applied.

25. A method of killing a pest, the method comprising:

providing a treatment enclosure containing pests or their eggs, or an article infested with pests or their eggs, the treatment enclosure comprising a structure for fully or partially sealing the treatment enclosure, the structure comprising a flexible outer layer that is impermeable or substantially impermeable to pesticidal vapors;

providing a substrate impregnated with a pesticidal composition; and

passively releasing pesticidal vapors of the pesticidal composition from the substrate within the treatment enclosure for a treatment period, wherein the pesticidal composition comprises neem oil;

wherein the concentration of neem oil in the pesticidal composition comprises in the range of about 0.00055% to 0.013% by volume per volume of the treatment enclosure.

26. A method of controlling a pest by killing the pest, the method comprising:

providing a treatment enclosure containing pests or their eggs, or an article infested with pests or their eggs, the treatment enclosure comprising a structure for fully or partially sealing the treatment enclosure, the structure comprising a flexible outer layer that is impermeable or substantially impermeable to pesticidal vapors;

providing a substrate impregnated with a pesticidal composition; and

passively releasing pesticidal vapors of the pesticidal composition from the substrate within the treatment enclosure for a treatment period, wherein the pesticidal composition comprises neem oil.

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded May 5, 2021
From: VENTURE LENDING & LEASING VIII, INC.
To: 0903608 B.C. LTD.
Reel/Frame 056147/0829 →
SECURITY INTEREST Recorded Oct 20, 2017
From: 0903608 B.C. LTD.
To: VENTURE LENDING & LEASING VIII, INC.
Reel/Frame 044255/0893 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2016
From: TERRAMERA, INC.
To: 0903608 B.C. LTD.
Reel/Frame 038934/0671 →
CORRECTIVE ASSIGNMENT TO CORRECT THE FIRST ASSIGNOR EXECUTION DATE PREVIOUSLY RECORDED AT REEL: 038637 FRAME: 0818. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded May 25, 2016
From: MANHAS, KARAN; ROZEK, ANNETT; WOODBURY, NATHAN; LENTZ, SHANNON; TAKEUCHI, ROBERT JAMES ETSU; OZEROFF, SASHA
To: TERRAMERA, INC.
Reel/Frame 038814/0070 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2016
From: MANHAS, KARAN; ROZEK, ANNETT; WOODBURY, NATHAN; LENTZ, SHANNON; TAKEUCHI, ROBERT JAMES ETSU; OZEROFF, SASHA
To: TERRAMERA, INC.
Reel/Frame 038637/0818 →
Continuity (7)
Provisional Application 62008425 · Jun 5, 2014
Provisional Application 61941049 · Feb 18, 2014
Provisional Application 61918641 · Dec 19, 2013
Provisional Application 61913194 · Dec 6, 2013
Provisional Application 61911434 · Dec 3, 2013
Provisional Application 61905415 · Nov 18, 2013
Related Publication 20160286782A1 · Oct 6, 2016
References Cited (223)
US 1003393A · Bauer · 1911 [cited by applicant]
US 2058177A · Raff · 1936 [cited by applicant]
US 2396054A · McKim · 1946 [cited by applicant]
US 2793154A · Shillitoe et al. · 1957 [cited by applicant]
US 2897112A · Hartford et al. · 1959 [cited by applicant]
US 2979268A · Brun · 1961 [cited by examiner]
US 3169705A · Geiger · 1965 [cited by applicant]
US 3630446A · Roth · 1971 [cited by applicant]
US 3771254A · Scott · 1973 [cited by applicant]
US 3996348A · Greenberg · 1976 [cited by applicant]
US 4123518A · Behrenz · 1978 [cited by applicant]
US 4202472A · Lin · 1980 [cited by applicant]
US 4283878A · Hill et al. · 1981 [cited by applicant]
US 4400909A · Reese · 1983 [cited by applicant]
US 4556562A · Larson · 1985 [cited by applicant]
US 4576844A · Murray · 1986 [cited by examiner]
US 4804142A · Riley · 1989 [cited by applicant]
US 4817824A · LaFleur · 1989 [cited by examiner]
US 4923745A · Wolfert · 1990 [cited by applicant]
US 4943434A · Lidert · 1990 [cited by applicant]
US 5001146A · Carter et al. · 1991 [cited by applicant]
US 5060597A · Fredericks · 1991 [cited by applicant]
US 5145604A · Neumiller · 1992 [cited by applicant]
US 5405612A · Locke et al. · 1995 [cited by applicant]
US 5472700A · Staetz et al. · 1995 [cited by applicant]
US 5679662A · Chang et al. · 1997 [cited by applicant]
US 5738863A · Sackin et al. · 1998 [cited by applicant]
US 5792465A · Hagarty · 1998 [cited by applicant]
US 5885600A · Blum et al. · 1999 [cited by applicant]
US 5900244A · Howse · 1999 [cited by applicant]
US 5961043A · Samuelson · 1999 [cited by applicant]
US 6294571B1 · Subbaraman et al. · 2001 [cited by applicant]
US 6339897B1 · Hayes · 2002 [cited by applicant]
US 6610254B1 · Furner · 2003 [cited by applicant]
US 6641827B2 · Yoshida et al. · 2003 [cited by applicant]
US 6646014B2 · Watkins · 2003 [cited by applicant]
US 6703034B2 · Parmar et al. · 2004 [cited by applicant]
US 6849614B1 · Bessette · 2005 [cited by applicant]
US 6942835B2 · Monblanc · 2005 [cited by applicant]
US 6949587B1 · Bessette · 2005 [cited by applicant]
US 7381431B2 · Baker et al. · 2008 [cited by applicant]
US 7402302B2 · Plato · 2008 [cited by applicant]
US 7497623B2 · Thomas · 2009 [cited by applicant]
US 7687533B2 · Critcher et al. · 2010 [cited by applicant]
US 7955609B2 · Baron et al. · 2011 [cited by applicant]
US 8012554B2 · Shelley · 2011 [cited by applicant]
US 8105620B2 · Williams · 2012 [cited by applicant]
US 8119150B2 · Tamarkin et al. · 2012 [cited by applicant]
US 8707616B1 · Black · 2014 [cited by applicant]
US 9999218B2 · Manhas · 2018 [cited by examiner]
US 20030168521A1 · Skalitzky · 2003 [cited by applicant]
US 20030224939A1 · Miles · 2003 [cited by applicant]
US 20040034149A1 · Garcia · 2004 [cited by examiner]
US 20050220374A1 · Thomas · 2005 [cited by applicant]
US 20060121073A1 · Goyal · 2006 [cited by applicant]
US 20060130391A1 · Livingston · 2006 [cited by examiner]
US 20060276339A1 · Windsor · 2006 [cited by examiner]
US 20070134127A1 · Smith · 2007 [cited by applicant]
US 20080250698A1 · Chadha · 2008 [cited by applicant]
US 20080269177A1 · Bessette · 2008 [cited by applicant]
US 20090235949A1 · Ritterband · 2009 [cited by applicant]
US 20090257958A1 · Sims · 2009 [cited by applicant]
US 20100120724A1 · Bessette · 2010 [cited by applicant]
US 20100158965A1 · Beitzel · 2010 [cited by examiner]
US 20100264232A1 · Gruenbacher · 2010 [cited by applicant]
US 20110070308A1 · Williams et al. · 2011 [cited by applicant]
US 20110113674A1 · Levy · 2011 [cited by applicant]
US 20110164834A1 · Stiglic · 2011 [cited by applicant]
US 20110229589A1 · Elraz · 2011 [cited by applicant]
US 20120171313A1 · Boone · 2012 [cited by applicant]
US 20120181349A1 · Adleff · 2012 [cited by applicant]
US 20130295153A1 · Miresmailli · 2013 [cited by applicant]
US 20140048614A1 · Santini · 2014 [cited by applicant]
US 20140048620A1 · Semenov · 2014 [cited by applicant]
US 20140166774A1 · Morhain · 2014 [cited by applicant]
US 20140208636A1 · Black · 2014 [cited by applicant]
US 20140209698A1 · Olchovy · 2014 [cited by examiner]
US 20140220164A1 · Manhas et al. · 2014 [cited by applicant]
US 20140242138A1 · Kritzman · 2014 [cited by applicant]
US 20140242199A1 · Manhas et al. · 2014 [cited by applicant]
US 20140335140A1 · Hoag · 2014 [cited by applicant]
CA 2066527C · 1992 [cited by applicant]
CA 2068039A1 · 1993 [cited by applicant]
CA 2237484A1 · 1998 [cited by applicant]
CA 2677936C · 2011 [cited by applicant]
CA 2849270A1 · 2013 [cited by applicant]
CN 1276161C · 2000 [cited by applicant]
CN 1322110C · 2001 [cited by applicant]
CN 1513319A · 2004 [cited by applicant]
CN 1633849A · 2005 [cited by applicant]
CN 101296710A · 2008 [cited by applicant]
CN 101442908A · 2009 [cited by applicant]
CN 101448394A · 2009 [cited by applicant]
CN 101537044A · 2009 [cited by applicant]
CN 102091337A · 2011 [cited by applicant]
CN 102171321A · 2011 [cited by applicant]
DE 1230259B · 1966 [cited by applicant]
DE 2026119A1 · 1970 [cited by applicant]
DE 1694240A1 · 1971 [cited by applicant]
DE 1954501A1 · 1971 [cited by applicant]
DE 2028226A1 · 1971 [cited by applicant]
DE 091898A1 · 1972 [cited by applicant]
DE 2231099A1 · 1974 [cited by applicant]
DE 2145318A1 · 1974 [cited by applicant]
DE 8812770U1 · 1988 [cited by applicant]
EP 0019010A1 · 1980 [cited by applicant]
EP 0218162A2 · 1987 [cited by applicant]
EP 494067A1 · 1992 [cited by applicant]
EP 948892A1 · 1999 [cited by applicant]
EP 2250904A1 · 2010 [cited by applicant]
GB 2405340A · 2005 [cited by applicant]
JP S5042053 · 1975 [cited by applicant]
JP 6396101A · 1988 [cited by applicant]
JP 6438006 · 1989 [cited by applicant]
JP 4308511 · 1992 [cited by applicant]
JP 5139907A · 1993 [cited by applicant]
JP 610122B2 · 1994 [cited by applicant]
JP 8267086 · 1996 [cited by applicant]
JP 2000247809A · 2000 [cited by applicant]
JP 2000281509A · 2000 [cited by applicant]
JP 2001199807A · 2001 [cited by applicant]
JP 2002511391A · 2002 [cited by applicant]
JP 2002521406A · 2002 [cited by applicant]
JP 200312411A · 2003 [cited by applicant]
JP 2005513053A2 · 2005 [cited by applicant]
JP 2005255664A · 2005 [cited by applicant]
JP 2006306835A · 2006 [cited by applicant]
JP 2010515775A · 2010 [cited by applicant]
JP 2010522236A · 2010 [cited by applicant]
JP 2011517685A · 2011 [cited by applicant]
TW 201306740A1 · 2013 [cited by applicant]
WO 9747193 · 1997 [cited by applicant]
WO 0005964A1 · 2000 [cited by applicant]
WO 0100034A1 · 2001 [cited by applicant]
WO 03028456A1 · 2003 [cited by applicant]
WO 2009038599A1 · 2009 [cited by applicant]
WO 2009144712A2 · 2009 [cited by applicant]
WO 2011029754A3 · 2011 [cited by applicant]
WO 2012107266A1 · 2012 [cited by applicant]
WO 2013050967A1 · 2013 [cited by applicant]
WO 2013063534A1 · 2013 [cited by applicant]
S. Michaelraj & R.K. Sharma, Fumigant Toxicity of Neem Formulations Against Sitophilus oryzae and Rhyzopertha dominica, 2 J Agricult. Tech. (Year: 2006). [cited by examiner]
Gunter Schmal, et al, The Efficacy of Neem Seed Extracts (Tre-san, MiteStop) on a Broad Spectrum of Pests and Parasites, 107 Parasitol. Res. 261 (Year: 2010). [cited by examiner]
Samir Tine, et al, Laboratory Evaluation of Azadirachtin Against the Oriental Cockroach, [cited by examiner]
Gahukar, R.T., “Formulations of neem based products/pesticides”, Pestology, 1996, 20(9):44-45. [cited by applicant]
Gochev, V., et al., “Chemical composition and antimicrobial activity of Bulgarian peppermint oils”, Bulgaria Scientific Papers, 2008, 36(5):83. [cited by applicant]
Granger Passet, “Thymus vulgaris spontane de France: Races chimiques et chemotaxonomie”, Phytochemistry, 1973, 12(7):1683-1691. [cited by applicant]
Harwood, S.H., et al., “Toxicity of peppermint monoterpenes to the variegated cutworm (Lepidoptera: Noctuidae)”, J. Econ. Entomol, 1990, 83:1761-1767. [cited by applicant]
Hierro, I., et al., “Action of different monoterpenic compounds against Anisakis simplex S.I.L. larvae”, Phytomedicine, 2004, 11:77-82. [cited by applicant]
Hui, L., et al., “Chemical composition of lavender essential oil and its antioxidant activity and inhibition against rhinitis-related bacteria”, Afri. J. of Micro. Res., 2010, 4(4):309-313. [cited by applicant]
Hummelbrunner, A.L., et al., “Acute, sublethal, antifeedant and synergistic effects of monoterpenoid essential oil compounds on the tobacco cut worm (Lepidoptera: Noctuidae)”, J. Agric. Food Chem., 2001, 49:715-720. [cited by applicant]
Isman, M.B., et al., “Pesticides based on plant essential oils: from traditional practice to commercialization”, Naturally Occurring Bioactive Compounds, 2006, 3(2):29-44. [cited by applicant]
Jones, C. and Fim, R., “Some allelochemicals of Ptteridium aquilinum and their involvement in resistance to Pieris brassicae”, Biochem. Syst. Ecol, 1979, 7:187-192. [cited by applicant]
Karr, L.L. and Coats, J.R., “Effects of four monoterpenoids on growth and reproduction of the German cockroach (Blattodea: Blattellidae)”, J. Econ. Entomol, 1992, 85:424-429. [cited by applicant]
Kaul, P.N., et al., Volatile constituents of essential oils isolated from different parts of cinnamon ( [cited by applicant]
Khattak, M.K., et al., “Repellency and residual effect of neem or mineral oil on the distribution and oviposition of maize weevil, [cited by applicant]
Kim, E.H., et al., “Acaricidal activity of clove bud oil compounds against Dermatophagoides farinae and Dermatophagoides pteronyssinus (Acari: Pyroglyphidae)”, J. Agric Food Chem, 2003, 51:885-889. [cited by applicant]
Kimbaris, A.C., et al., “Quantitative analysis of garlic ( [cited by applicant]
Lee, S., et al., “Insecticidal activity of monoterpenoids to western corn root worm (Coleoptera: Chrysomelidae), spotted spidermite (Acari: Tetranychidae) and Housefly (Diptera: Muscidae)”, J. Econ. Entomol, 1997, 90:88… [cited by applicant]
Lota, M.L., et al., “Volatile components of peel and leaf oils of lemon and lime species”, J. Agri. Food Chem., 2002, 50:796-805. [cited by applicant]
Marcus C. and Lichtenstien, P., “Biologically active components of anise: toxicity and interactions with insecticides in insects”, J. Agri. Food Chem., 1979, 27(6):1217-1223. [cited by applicant]
Miresmailli, S., et al., “Comparative toxicity of [cited by applicant]
Mishra, A.K., et al., “Use of neem oil as a mosquito repellent in tribal villages of mandla district, madhya pradesh”, Indian J Malariol, 1995, 32(3):99-103. [cited by applicant]
Momen, F.M., et al., “Influence of mint and peppermint on Tetrynychus urticae and some predacious mites of the Family Phytoseiidae (Acari: Tetranychidae: Phytoseiidae)”, Acta Phytopathologica et Entomologica Hungaria, 2… [cited by applicant]
Naqvi, S.N.H., et al., “Comparative toxicity of RB-A [Neem Formulation] and Malathion against bed bugs”, Proceedings of Pakistan Congress of Zoology, 1993, 13:369-377. [cited by applicant]
National Research Council, Board on Science and Technology for International Development, Ad Hoc Panel Report, Neem: A Tree for Solving Global Problems, Washington: National Academy Press, 1992. [cited by applicant]
Obeng-Ofori, D., et al., “Bioactivity of eugenol, a major component of essential oil of Ocimum suvae (wild) against four species of stored product coleopteran”, Int. J. Pest Manag. 1997, 43:89-94. [cited by applicant]
Pavela, R., et al., “Effectiveness of Neem ( [cited by applicant]
Perrucci, S., et al., “Therapeutic efficacy of linalool for the topical treatment of parasitic otitis caused by Psoroptes cuniculi in the rabbit and in the goat”, Med. Vet. Entomol, 1997, 11:300-302. [cited by applicant]
Product labels for Cirkil CX and Cirkil RTU products, first sold in the United States on or about Jun. 25, 2012. [cited by applicant]
Rahman, A and Talukder, F.A., “Bioefficacy of some plant derivatives that protect grain against the pulse beetle, [cited by applicant]
Rajeswara, Rao, B.R., et al., “Volatile flower oils of three genotypes of rose-scented geranium ( [cited by applicant]
Romero, A., et al., “Insecticide resistance in the bed bug: a factor in the pests sudden resurgence”, J Med Entomol, 2007, 44(2):175-178. [cited by applicant]
Salom, S.M., et al., “Laboratory evaluation of biologically-based compounds as antifeedants for the pales weevil, hulobius-pale (Herbst)”, J. Entomol, Sci., 1994, 29:407-419. [cited by applicant]
Samarasekera, R., “Mosquitocidal activity of leaf and bark essential oils of Ceylon Cinnamomum zeylanicum”, Journal of Essential Oil Research, 2005, 17(3):301-303. [cited by applicant]
Santos, P.M., et al., “Essential oils from hairy root cultures and fruits and roots of Pimpinella anisum”, Phytochemistry, 1998, 48:455-460. [cited by applicant]
Schmahl, G., et al., “The efficacy of neem seed extracts (Tre-San, MiteStop) on broad spectrum of pests and parasites”, Parasitology Research, 2010, 107(2):261-269. [cited by applicant]
Schmutterer, H. “Properties and potential of natural pesticides from the neem tree, [cited by applicant]
Shabnum, S. and Wagay, M., “Essential oil composition of [cited by applicant]
Shellie, R., et al., “Characterisation of lavender essentail oils by using gas chromatography-mass spectrometry with correlation of linear retention indices and comparison with comprehensive two-dimensional gas chromato… [cited by applicant]
Simic, A., et al., “The chemical composition of some Lauraceae essential oils and their antifungal activities”, Phytother. Res. 2004, 18:713-717. [cited by applicant]
Thompson, J., et al., “Qualitative and quantitative variation in monoterpene co-occurrence and composition in the essential oil of Thymus vulgaris chemotypes”, J. Chem Ecol, 2003, 29:859. [cited by applicant]
Toncer, O., et al., “Changes in essential oil composition of oregano ( [cited by applicant]
Traboulsi, A.F., et al., “Insecticidal properties of essential plant oils against the mosquito [cited by applicant]
Tripathi, A.K., et al., “Effects of volatile oil constituents of Mentha species against stored grain pests, [cited by applicant]
Tripathi, A.K., et al., “Toxicity, feeding deterrence, and effect of activity of 1, 8-cineole from Artemisia annua on progeny production of Tribolium castanaeum (Coleoptera: Tenebrionidae)”, J. Econ. Entomol, 2001, 94:9… [cited by applicant]
Trongtokit Y., et al., “Comparative repellency of 38 essential oils against mosquito bites”, Phytotherapy Res, 2005, 19:303-309. [cited by applicant]
Vasudeva, N. and Sharma, T., “Chemical composition and antimicrobial activity of essential oil of citrus limettioides Tanaka”, Journal of Pharmaceutical Technology and Drug Research, 2012, 1(1):2. [cited by applicant]
Vokou, D., et al., “Geographic variation of Greek oregano ( [cited by applicant]
Webb, et al, “On the penetration of insecticides through the insect cuticle” (Cooper Technical Bureau: Berkhamsted), Journal of Experimental Biology, 1945, 22:8-20. [cited by applicant]
Xia, Y., et al., “The molecular and cellular bassis of olfactory-driven behaviour in Anopheles gambiae larvae”, Proceedings of the National Academy of Sciences of the USA, 2008, 105:6433-6438. [cited by applicant]
Yang, Y.C. et al., “Ovicidal and adulticidal effects of Eugenia caryophyllata bud and leaf oil compound on Pediculus capitis”, J Agri Food Chem, 2003, 51:4884-4888. [cited by applicant]
Yang, Y.C., et al., Ovicidal and adulticidal activities of Cinnamomum zeylanicum bark essential oil compounds and related compounds against Pediculus humanus capitis (Anoplura: Pediculidae), Int J Parasitol, 2005, 35:15… [cited by applicant]
“Animal Health Farms Products—Checkmite”. Accessed Dec. 10, 2016. <http://animal health.bayer.ca/en/farms/heckmite/>. [cited by applicant]
“Apiguard: Varroa control Vita Europe”. Accessed Oct. 12, 2016. <http://www.vita-europe.com/products/apiguard/>. [cited by applicant]
“Apistan: Varroa control Vita Europe”. Accessed Dec. 10, 2016. <http://www.vita-europe.com/products/apistan/>. [cited by applicant]
Apivar Varroa Mite Strips. Accessed Dec. 10, 2016. <http://apivar.co/nz>. [cited by applicant]
Guzman-Novoa, E, et al, “Varroa destructor is the main culprit for the death and reduced populations of overwintered honey bee ( [cited by applicant]
Melathopoulos, AP, et al, “Field evaluation of neem and canola oil for the selective control of the honey bee (Hymenoptera: Apidae) mite parasites [cited by applicant]
“Mite Away Quick Strips—NOD Apiary Products”. Accessed Oct. 13, 2016. <http://nodglobal/com/mite-away-quick-strips/. [cited by applicant]
“Mite Gone for Effective Control of the Varroa & Tracheal Mites”. Accessed Oct. 13, 2016. <http:/www.mitegone.com/>. [cited by applicant]
Thompson, HM, et al, “First report of varroa destructor resistance to pyrethroids in the UK”, Apidologie, 2002, 33(4):357-366. [cited by applicant]
“Thymovar”. Accessed Dec. 10, 2016. <http://biovet.ch/en/lmkerei/thymovar.html>. [cited by applicant]
Abbassy, M.A., et al., “Insecticidal and synergistic effects of Majorana hortensis essential oil and some of its major constituents”, Entomologia Experimentalis et Applicata, 2009, 131(3):225-232. [cited by applicant]
Ahmed, K.S., et al., “Effects of plant oils on oviposition preference and larval survivorship of Callosobruchus chinesis on azuki bean”, Applied Entomology and Zoology, 1999, 34(4):547-550. [cited by applicant]
Ansari, M.A., et al. “Larvicidal and mosquito repellent action of peppermint ( [cited by applicant]
Arslan, N., et al., “Variation in essential oil content and composition in Turkish anise ( [cited by applicant]
Avato, P., et al., “Allysulfide constituents of garlic volatile oil as antimicrobial agents”, Phytomedicine, 2000, 7(3):239-243. [cited by applicant]
Barnard, D.R., “Repellency of essential oils to mosquitoes ( [cited by applicant]
Brahmachari, G., “Neem—an omnipotent plant: a retrospection”, Chembiochem, 2004, 5:408-421. [cited by applicant]
Chaieb, K., et al., “The chemical composition and biological activity of clove essential oil, Eugenia caryophyllata ( [cited by applicant]
Chang, K.S. and Ahn, Y.T., “Fumigant activity of {E)—anethole identified in Illicium verum fruit against Blatella germanica”, Pest Manage. Sci., 2001, 58:161-166. [cited by applicant]
Chang, S.T. and Cheng, S.S., “Antitermitic activity of leaf essential oils and components from Cinnamomum osmophleum”, J. Agric. Food Chem., 2002, 50:1389-1392. [cited by applicant]
Chastrette, M., et al., “Approach to general classification of solvents using a multivariate statistical treatment of quantitative solvent parameters”, Journal of the American Chemical Society, 1985, 107(1):1520-1526. [cited by applicant]
Cheng, S.S., et al., “Variations in insecticidal activity and chemical compositions of leaf essential oils from Cryptomeria japonica at different ages”, Bioresource Tech., 2009, 100(1):465-470. [cited by applicant]
Choi, W., et al., Toxicity of plant essential oils to Tetranychus urticae (Acari:Tetranychidae) and Phytoseiulus persimilis (Acari:Phytoseiidae), Journal of Economic Entomology, 2004, 97(2):553-558. [cited by applicant]
Clark, R.J. and Menary, R.C., “Variations in compositions of peppermint oil in relation to production areas”, Econ. Bot., 1981, 35:59-69. [cited by applicant]
Daniel, S.H. and Smith, R.H., “The repellent effect of neem ( [cited by applicant]
Don-Pedro, K.M., “Investigation of single and joint fumigant insecticidal action of citrus peel oil components”, Pestic. Sci., 1996, 46:79-84. [cited by applicant]
Ellis, M.D., and Baxendale, F.P., “Toxicity of seven monoterpenoids to tracheal mites (Acari: Tarsonemidae) and their honey bee (Hymenoptera: Apidae) hosts when applied as fumigants”, J. Econ. Entomol, 1997, 90:1087-109… [cited by applicant]
Erbilgin, et al., “Acetophenone as an anti-attractant for the Western Pine Beetle, [cited by applicant]
Franzios, G., et al., “Insecticidal and genotoxic activities of mint essential oils”, J. Agric. Food Chem., 1997, 45:2690-2694. [cited by applicant]
Fuhremann, T.W., et al.,. “Effects of naturally occurring food plant components on insecticide degradation in rats”, J. Agri. Food Chem., 1978, 26(5):1068-1075. [cited by applicant]