IP Library Granted Patent US 10,925,503
Granted Patent B2
US 10,925,503 · App. 15/037,595 · Granted Feb 23, 2021

Saturation-tolerant electrophysical recording interface

Inventors: Vaibhav Karkare (San Jose, CA); Dejan Markovic (Palo Alto, CA)
Assignee: The Regents of the University of California
A61B5/04017A61B5/0402A61B5/0428A61B5/0476A61B5/0488H03K3/0315H03K5/1565
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Quick Facts
Patent No.
US 10,925,503
App. No.
15/037,595
Granted
Feb 23, 2021
Kind
B2
Abstract

Signal recording sensor systems in accordance with embodiments of the invention include sensors capable of sensing and capturing electrophysiological signals in the presence of interference signals, an analog front-end including circuitry configured to record electrophysiological input signals as a voltage, and an analog to digital converter including a voltage-controlled-oscillator configured to convert the recorded analog electrophysiological input signal to a phase output. While such signal recording sensor systems can be used in the recording of biosignals and/or electrophysiological signals generated from living organisms, signal recording sensor systems in accordance with embodiments of the invention are not limited to recording biosignals and/or electrophysiological signals.

Claims (39)

1. A signal recording sensor system comprising:

at least one sensor capable of sensing at least one input signal in the presence of an interference signal, where the at least one sensor is configured to capture the at least one input signal;

an analog front-end comprising circuitry configured to record the at least one input signal;

an analog to digital converter comprising a voltage-controlled-oscillator configured to convert the recorded analog input signal to a phase output;

wherein the voltage-controlled-oscillator is a differential voltage-controlled-oscillator configured to be duty-cycled according to a particular duty-cycling ratio, and

wherein the voltage-controlled-oscillator is configured to select the particular duty-cycling ratio to target different types of signals within the signal recording sensor system.

2. The system of claim 1 , wherein the at least one input signal comprises an electrophysiological signal.

3. The system of claim 1 , wherein the analog to digital converter is further configured to operate according to a timing sequence for harmonic-mode suppression.

4. The system of claim 3 , wherein the timing sequence for harmonic-mode suppression prevents harmonic oscillation modes utilizing a set of timing signals, and wherein the set of timing signals comprise:

a first timing signal at which oscillator nodes of the differential voltage-controlled-oscillator are pre-charged to deterministic values; and

a second timing signal at which a high-voltage pulse is applied to a fixed location of the differential voltage-controlled-oscillator.

5. The system of claim 3 , wherein the timing sequence for harmonic-mode suppression includes a dynamic element matching implementation.

6. The system of claim 5 , wherein the dynamic element matching implementation comprises the addition of a pseudo-random dither between a first timing signal and a second timing signal in the timing sequence for harmonic-mode suppression.

7. The system of claim 6 , wherein:

the first timing signal is when high-voltage pulse is applied to a fixed location of the differential voltage-controlled-oscillator; and

the second timing signal is when a counting process for the differential voltage-controlled-oscillator is started.

8. The system of claim 1 , wherein the differential voltage-controlled-oscillator comprises a front end that provides opposite polarity inputs to two ring oscillators.

9. The system of claim 1 , wherein the digital output signal is subject to a first-order digital high-pass filter prior to final digital output.

10. The system of claim 1 , wherein the system further comprises a polynomial correction engine that is configured to perform polynomial fits on the digital output.

11. The system of claim 1 , wherein the sensor system further comprises coarse and fine counting circuitry.

12. The system of claim 11 , wherein the coarse and fine counting circuitry is configured to generate a fine count based on (1) initial and final locations on the voltage-controlled-oscillator identified during a period and (2) the polarity of a transitioning inverter in the voltage-controlled-oscillator.

13. The system of claim 11 , wherein the coarse and fine counting circuitry is configured to generate a coarse count based on a number of periods of the voltage-controlled-oscillator.

14. The system of claim 1 , wherein the analog front-end is further configured to record the at least one input signal as a voltage.

15. The system of claim 1 , wherein the analog to digital converter comprising the voltage-controlled-oscillator is further configured to convert the recorded analog input signal to a current output prior to converting the recorded analog input signal to the phase output.

16. The system of claim 1 , wherein the analog front-end comprising circuitry is further configured to record the at least one input signal as a current.

17. The system of claim 1 , wherein the at least one sensor comprises an environmental sensor, and wherein the at least one input signal comprises an environmental signal.

18. The system of claim 1 , wherein the differential voltage-controlled-oscillator is duty-cycled to reduce power requirements.

19. The system of claim 1 , wherein the duty-cycling ratio is at least 5%.

20. A signal recording sensor system comprising:

at least one sensor capable of sensing at least one electrophysiological input signal in the presence of an interference signal, where the at least one sensor is configured to capture the at least one electrophysiological input signal;

an analog front-end comprising circuitry configured to record the at least one electrophysiological input signal as a voltage;

an analog to digital converter comprising a differential voltage-controlled-oscillator configured to convert the recorded analog electrophysiological input signal to a phase output,

wherein the differential voltage-controlled-oscillator is configured to be duty-cycled according to a particular duty-cycling ratio,

wherein the differential voltage-controlled-oscillator is configured to operate according to a timing sequence for harmonic-mode suppression that utilizes a set of timing signals, the set of timing signals comprising:

a first timing signal at which oscillator nodes of the differential voltage-controlled-oscillator are pre-charged to deterministic values, and

a second timing signal at which a high-voltage pulse is applied to a fixed location of the differential voltage-controlled-oscillator; and

a coarse and fine counting circuitry configured to:

generate a fine count based on (1) initial and final locations on the differential voltage-controlled-oscillator identified during a period and (2) the polarity of a transitioning inverter in the differential voltage-controlled-oscillator, and

generate a coarse count based on a number of periods of the voltage-controlled-oscillator.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE NAME OF THE RECEIVING PARTY PREVIOUSLY RECORDED ON REEL 038637 FRAME 0885. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 13, 2021
From: KARKARE, VAIBHAV; MARKOVIC, DEJAN
To: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 055726/0669 →
CONFIRMATORY LICENSE Recorded Jan 5, 2017
From: UNIVERSITY OF CALIFORNIA, LOS ANGELES
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 041257/0201 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 18, 2016
From: KARKARE, VAIBHAV; MARKOVIC, DEJAN
To: REGENTS OF THE UNIVERSITY OF CALIFORNIA
Reel/Frame 038637/0885 →
Continuity (2)
Provisional Application 61905955 · Nov 19, 2013
Related Publication 20160287121A1 · Oct 6, 2016