IP Library Granted Patent US 10,174,378
Granted Patent B2
US 10,174,378 · App. 15/069,952 · Granted Jan 8, 2019

Gene expression monitoring for risk assessment of apple and pear fruit storage stress and physiological disorders

Inventors: David R. Rudell, Jr. (Wanatchee, WA); Rachel S. Leisso (Wanatchee, WA); James P. Mattheis (Wanatchee, WA); James J. Giovannoni (Ithaca, NY); Nigel E. Gapper (Dryden, NY); Nicolai M. Bart (Heusden, BE); Chris B. Watkins (Ithaca, NY); Jason W. Johnston (Havelock North, NZ); Maarten L. Hertog (Scherpenheuvel, BE); Robert J. Schaffer (Auckland, NZ)
Assignees: The United States of America, as represented by the Secretary of Agriculture; Cornell University; The New Zealand Institute for Plant and Food Research; Katholieke Universiteit
C12Q1/6883C12Q1/6895G06F19/18G06F19/20G06F19/22G06N5/048C12Q2600/118C12Q2600/13C12Q2600/158
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Quick Facts
Patent No.
US 10,174,378
App. No.
15/069,952
Granted
Jan 8, 2019
Kind
B2
Abstract

The present invention is a tool for diagnosis and prediction using biomarker-based risk assessment for chilling-related disorders of Rosaceous fruit crops including apple and pear. Provided are methodology and genes whose relative and absolute expression can accurately indicate disorder risk throughout the production and supply chain of these crops. This technology describes a necessary and novel management tool for stakeholders producing, servicing, or retailing these crops.

Claims (4)

1. A method comprising:

a) isolating mRNA from peel tissue or cortex tissue of at least one apple or at least one pear;

b) performing reverse transcription PCR on said isolated mRNA; and

c) assaying the level of expression of a set of biomarkers, wherein the set of biomarkers consists of: MDP0000848515, MDP0000238780, MDP0000260007, MDP0000153149, MDP0000585315, MDP0000273646, MDP0000216786, MDP0000180580, MDP0000737425, MDP0000298967, MDP0000808492, MDP0000273866, MDP0000353053, MDP0000910032, MDP0000145050, MDP0000263844, MDP0000158999, MDP0000547254, MDP0000196325, MDP0000224653, MDP0000321382, MDP0000270602, MDP0000233661, MDP0000665342, MDP0000246831, MDP0000823528, MDP0000408705, MDP0000518327, MDP0000291249, MDP0000154589, MDP0000202817, MDP0000590954, MDP0000312397, MDP0000213383, MDP0000529726, MDP0000312071, MDP0000639894, MDP0000307665, MDP0000183676, MDP0000754521, MDP0000797616, MDP0000818877, MDP0000782908, MDP0000266443, MDP0000562305, MDP0000228366, MDP0000361351, MDP0000737001, MDP0000412192, MDP0000223032, MDP0000149492, MDP0000264361, MDP0000125882, MDP0000498460, MDP0000163006, MDP0000225132, MDP0000329063, MDP0000170865, MDP0000665685, MDP0000196079, MDP0000200783, MDP0000182956, MDP0000862371, MDP0000321792, MDP0000441757, MDP0000313657, MDP0000599531, MDP0000297583, MDP0000272980, MDP0000317502, MDP0000268175, MDP0000722139, MDP0000637194, MDP0000125700, MDP0000287262, MDP0000745534, MDP0000164966, MDP0000389794, MDP0000318068, MDP0000322237, MDP0000225326, and MDP0000125411.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2018
From: WATKINS, CHRIS; GAPPER, NIGEL E.
To: CORNELL UNIVERSITY
Reel/Frame 047390/0445 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2018
From: JOHNSTON, JASON WILLIAM; SCHAFFER, ROBERT JAMES
To: THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEARCH LIMITED
Reel/Frame 047288/0550 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2016
From: RUDELL, DAVID R., JR.
To: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Reel/Frame 040040/0514 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2016
From: LEISSO, RACHEL S.
To: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Reel/Frame 040041/0023 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2016
From: MATTHEIS, JAMES P.
To: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Reel/Frame 040041/0074 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2016
From: GIOVANNONI, JAMES J.
To: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Reel/Frame 039754/0902 →
Continuity (1)
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