IP Library › Granted Patent US 10,086,091
Granted Patent B2
US 10,086,091 · App. 15/080,165 · Granted Oct 2, 2018

Method of preparation of biodegradable nanoparticles with recognition characteristics

Inventors: Nicholas Peppas (Austin, TX); Heidi Culver (Austin, TX)
Assignee: Board of Regents, The University of Texas System
A61K49/0093A61K49/0054C08F283/065A61K9/5146A61K9/5153
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,086,091
App. No.
15/080,165
Granted
Oct 2, 2018
Kind
B2
Abstract

The present disclosure relates to a novel type of recognitive biodegradable nanoparticles and their preparations. In particular, the present disclosure relates to combinations of MIPs and biodegradable nanoparticles.

Claims (3)

1. A composition comprising an outer shell having at least one binding cavity specific for a target molecule and wherein the outer shell comprises poly(maleic anhydride-alt-1-octadecene)-g-poly(ethylene glycol) methacrylate (PMAO-g-PEGMA); and a biodegradable inner core comprising poly(ε-caprolactone) (PCL) and substantially free of the binding cavity.

2. The composition of claim 1 , further comprising an active agent.

3. The composition of claim 2 , wherein the active agent is a fluorophore, a therapeutic agent, or a hydrophobic agent.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 14, 2017
From: PEPPAS, NICHOLAS A.; CULVER, HEIDI
To: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 044124/0123 →
CONFIRMATORY LICENSE Recorded May 13, 2016
From: UNIVERSITY OF TEXAS, AUSTIN
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 038704/0826 →
Continuity (3)
Continuation PCTUS2014057812 · Sep 26, 2014
Provisional Application 61883630 · Sep 27, 2013
Related Publication 20160199516A1 · Jul 14, 2016