IP Library Granted Patent US 10,031,152
Granted Patent B2
US 10,031,152 · App. 15/113,309 · Granted Jul 24, 2018

Automatic analyzer

Inventors: Yoshiki Muramatsu (Tokyo, JP); Takamichi Mori (Tokyo, JP); Kazuhiro Nakamura (Tokyo, JP)
Assignee: Hitachi High-Technologies Corporation
G01N35/1016G01N33/49G01N35/1011G01N35/1079G01N2035/1018
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Quick Facts
Patent No.
US 10,031,152
App. No.
15/113,309
Granted
Jul 24, 2018
Kind
B2
Abstract

A pressure sensor detects the inner pressure of a probe at the time of suction of a specimen and a memory stores therein a plurality of clogging detection parameters in accordance with pressure in the vacuum blood collection tube. The clogging detection parameter stored in the memory is selected in accordance with the pressure in the vacuum blood collection tube, and a determination of the clogging of the probe is performed based on the selected clogging detection parameter and the inner pressure at the time of suction of the specimen detected in the pressure sensor.

Claims (23)

1. An automatic analyzer comprising:

a vacuum blood collection tube having a cap and containing a specimen at a negative pressure therein;

a reaction cuvette;

a probe configured to pass through the cap of the vacuum blood collection tube, suck the specimen inside the vacuum blood collection tube, and discharge the specimen into the reaction cuvette;

a photometer configured to detect light that is transmitted through the reaction container containing a solution including the specimen;

a syringe causing the probe to suck and discharge the specimen;

a dispensation flow path connecting the syringe and the probe;

a pressure sensor arranged in the dispensation flow path and detecting an inner pressure of the probe;

a memory having stored therein a plurality of clogging detection parameters in accordance with a plurality of predetermined negative pressures for a same suction amount of the specimen; and

a controller configured to select one of the clogging detection parameters stored in the memory in accordance with the negative pressure in the vacuum blood collection tube, calculate a statistical distance between the selected clogging detection parameter and the inner pressure of the probe detected by the pressure sensor at the time of suctioning the specimen, and perform a clogging determination of the probe based on comparing the calculated statistical distance with a threshold value.

2. The automatic analyzer according to claim 1 , wherein the probe is determined to be clogged when the calculated statistical distance is outside the threshold value, and

wherein the probe is determined to not be clogged when the calculated statistical distance is within the threshold value.

3. The automatic analyzer according to claim 1 , wherein the controller is further configured to detect the negative pressure in the vacuum blood collection tube with the pressure sensor.

4. The automatic analyzer according to claim 2 , wherein the negative pressure in the vacuum blood collection tube is measured after passing of the probe through the cap and before suctioning the specimen.

5. The automatic analyzer according to claim 3 , wherein the negative pressure in the vacuum blood collection tube is measured after passing of the probe through the cap and before suctioning the specimen.

6. The automatic analyzer according to claim 4 , wherein the controller is further configured to measure the negative pressure in the vacuum blood collection tube by means of a suction operation of the syringe.

7. The automatic analyzer according to claim 5 , wherein the controller is further configured to measure the negative pressure in the vacuum blood collection tube by means of a suction operation of the syringe.

8. The automatic analyzer according to claim 4 , wherein the controller is further configured to control a lowering operation of the probe, and

wherein the probe is lowered at a first speed that is decreased or stopped when the probe passes through the cap to measure the negative pressure in the vacuum blood collection tube.

9. The automatic analyzer according to claim 5 , wherein the controller is further configured to control a lowering operation of the probe, and

wherein the probe is lowered at a first speed that is decreased or stopped when the probe passes through the cap to measure the negative pressure in the vacuum blood collection tube.

10. The automatic analyzer according to claim 8 , wherein the probe is lowered to a suction position at a second speed higher than the first speed after the negative pressure in the vacuum blood collection tube is measured.

11. The automatic analyzer according to claim 9 , wherein the probe is lowered to a suction position at a second speed higher than the first speed after the negative pressure in the vacuum blood collection tube is measured.

Assignments (2)
CHANGE OF NAME AND ADDRESS Recorded Mar 30, 2020
From: HITACHI HIGH-TECHNOLOGIES CORPORATION
To: HITACHI HIGH-TECH CORPORATION
Reel/Frame 052259/0227 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 21, 2016
From: MURAMATSU, YOSHIKI; MORI, TAKAMICHI; NAKAMURA, KAZUHIRO
To: HITACHI HIGH-TECHNOLOGIES CORPORATION
Reel/Frame 039214/0334 →
Priority Claims (1)
JP 2014-012070 · Jan 27, 2014 · national
Continuity (1)
Related Publication 20170010294A1 · Jan 12, 2017