Granted Patent
B2
US 10,087,444 · App. 15/118,551 · Granted Oct 2, 2018
MicroRNA composition for the treatment of neuroblastoma
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Abstract
Certain embodiments are directed to methods of identifying neuroblastoma differentiation-inducing compounds or agent and their use in treating neuroblastoma.
Claims (4)
1. A method of treating neuroblastoma comprising administering microRNA comprising a mature sequence of uaaggcacccuucugaguaga (SEQ ID NO: 1) and further comprising a seed sequence of aaggcac (SEQ ID NO: 3) to a subject having neuroblastoma.
2. The method claim 1 , wherein the microRNA is at most 150 nucleotides in length.
3. The method of claim 1 , wherein the microRNA is 17 to 130 nucleotides in length.
4. The method of claim 1 , wherein the microRNA further comprises a complementary region.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 16, 2017
From: DU, LUQIN
To: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
Reel/Frame 043309/0616 →
CONFIRMATORY LICENSE
Recorded Jun 26, 2017
From: UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 042986/0427 →
Continuity (2)
Provisional Application
61939730
· Feb 13, 2014