Systems and methods for tissue healing
Systems, methods and devices are provided for use in a negative pressure wound therapy system for healing a wound in a patient. Various aspects may include an ester-based material adapted to be directly applied to the wound, such as a smooth muscle fistula, without substantially damaging tissue in the wound during dressing changes. The ester-based material may have an affinity for the wound bed surface and/or wound fluid. In addition various aspects may include a device adapted to close the wound, such as a smooth muscle fistula.
1. A method of treating a wound bed including a smooth muscle fistula without causing substantial cellular disruption or damage, the method comprising:
applying an absorptive dressing comprising an ester-based foam having pores with a width of about 0.1 μm to about 80 μm directly to the wound bed including the smooth muscle fistula; and
applying a negative pressure to the absorptive dressing to thereby withdraw wound fluid from the wound bed.
2. The method of claim 1 , further comprising applying an occlusive material over the absorptive dressing to form a seal at the wound bed.
3. The method of claim 1 , wherein the absorptive dressing comprises secondary structural features within the ester-based foam and adapted to impart a flow pattern to the wound fluid being withdrawn from the wound bed.
4. The method of claim 1 , wherein the ester-based foam comprises at least two layers and wherein a first layer has an average pore size greater than an average pore size of a second layer.
5. The method of claim 1 wherein the ester-based foam has pores with a width of about 0.1 μm to about 50 μm.
6. A negative pressure treatment system for the treatment of a wound bed including a smooth muscle fistula, the negative pressure treatment system comprising:
an absorptive dressing comprising an ester-based foam adapted to be placed directly against the wound bed and to contact smooth muscle without causing substantial cellular disruption or damage in the negative pressure environment, the foam having primary structural features comprising pores with a width of about 0.1 μm to about 50 μm and secondary structural features adapted to direct a flow of wound fluid from the wound bed;
a vacuum pump configured to apply negative pressure to the absorptive dressing to thereby withdraw wound fluid from the wound bed; and
an interface layer adapted to be placed between the absorptive dressing and the wound bed.
7. The negative pressure treatment system of claim 6 , wherein the interface layer comprises an ester-based material.
8. The negative pressure treatment system of claim 7 , wherein the interface layer comprises a film having pores with a width of about 0.1 μm to about 50 μm.
9. A negative pressure treatment system for the treatment of a wound bed including a smooth muscle fistula, the negative pressure treatment system comprising:
an absorptive dressing comprising an ester-based foam layer;
an interface layer adjacent to the absorptive dressing;
wherein the absorptive dressing is adapted to be placed directly against the wound bed, and the interface layer is adapted for contacting smooth muscle without causing substantial cellular disruption or damage in the negative pressure environment, the foam having primary structural features comprising pores with a width of about 0.1 μm to about 50 μm and secondary structural features adapted to direct a flow of wound fluid from the wound bed; and
a vacuum pump configured to apply negative pressure to the absorptive dressing to thereby withdraw wound fluid from the wound bed.
10. The negative pressure treatment system of claim 9 , wherein the interface layer comprises an ester-based material.
11. The negative pressure treatment system of claim 10 , wherein the interface layer comprises a film having pores with a width of about 0.1 μm to about 50 μm.