IP Library Granted Patent US 10,071,976
Granted Patent B2
US 10,071,976 · App. 15/123,218 · Granted Sep 11, 2018

Small molecule fatty acid synthase inhibitors

Inventors: Nicholas D. P. Cosford (La Jolla, CA); Jeffrey Smith (La Jolla, CA)
Assignee: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
C07D277/46A61K31/426A61K31/427A61K31/5377C07D277/26C07D277/40C07D277/42C07D417/04C07D417/12
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Quick Facts
Patent No.
US 10,071,976
App. No.
15/123,218
Granted
Sep 11, 2018
Kind
B2
Abstract

Provided herein are small molecule Fatty Acid Synthase Inhibitors, compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds.

Claims (4)

1. A compound which has one of the following structures, or a pharmaceutically acceptable salt, or solvate thereof:

2. A compound which has one of the following structures, or a pharmaceutically acceptable salt, or solvate thereof:

3. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt, or solvate thereof, and at least one pharmaceutically acceptable diluent, excipient or binder.

4. A pharmaceutical composition comprising a compound of claim 2 , or a pharmaceutically acceptable salt, or solvate thereof, and at least one pharmaceutically acceptable diluent, excipient or binder.

Assignments (2)
CHANGE OF NAME Recorded Oct 18, 2017
From: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
To: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
Reel/Frame 044376/0651 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2017
From: COSFORD, NICHOLAS D.P.; SMITH, JEFFREY; ARDECKY, ROBERT J.; ZOU, JIWEN; MATTMANN, MARGRITH; TERIETE, PETER; LAMBERT, LESTER
To: SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE
Reel/Frame 041888/0322 →
Continuity (3)
Provisional Application 62110298 · Jan 30, 2015
Provisional Application 61949486 · Mar 7, 2014
Related Publication 20170066731A1 · Mar 9, 2017