IP Library › Patent Application 15132692
Patent Application
App. No. 15/132,692

CRYSTALLINE PHASES OF 5,6-DICHLORO-2-(ISOPROPYLAMINO)-(1-BETA-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE

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Quick Facts
Patent No.
US None
App. No.
15/132,692
Abstract

The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.

Claims (2)

1 . A crystalline solvate of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole, including a stoichiometric ratio of an organic solvent within a cavity of the crystal lattice, said solvent being selected from the group of: methanol, acetonitrile, ethyl acetate, diethylether, n-butylacetate, or 1-propanol, or mixtures thereof.

2 . Crystalline Form VI of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole, wherein said compound has unit cell parameters a=b=9.2825 Å, c=41.602 Å, and P4 1 2 1 2 space group (recorded at 296 K).

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 29, 2016
From: COQUEREL, GERARD; LEVILAIN, GUILLAUME; PETIT, MARIE-NOELLE; COSTE-LECONTE, SERVANTE
To: VIROPHARMA INCORPORATED
Reel/Frame 039294/0590 →
CHANGE OF NAME Recorded Jul 29, 2016
From: VIROPHARMA INCORPORATED
To: SHIRE VIROPHARMA INCORPORATED
Reel/Frame 039515/0196 →