Device and system of blood collection, and method thereof
A device for collecting a blood sample is provided. The device includes a collection unit, at least one capillary tube, a vacuum connector, and a storage unit. The collection unit has a top window for receiving the blood sample, a top surface, and a channel communicated with the top window. The at least one capillary tube is disposed in the collection unit and has a top end adjacent to the top window of the collection unit. The vacuum connector extends from the collection unit and communicates with the channel to provide a negative pressure by removing air in the channel. The storage unit is disposed under the collection unit for storing the blood sample.
1. A device for collecting a blood sample, comprising:
a collection unit comprising:
a top window;
a top surface;
a channel communicated with the top window;
at least one capillary tube having a top end adjacent to the top window;
wherein a distance between the top end of the at least one capillary tube and the top surface of the collection unit is in a range of 1.0 mm to 5.0 mm, such that the top end of the at least one capillary tube is used to contact with a blood drop from a puncture to continuously draw the blood flowing inside or along the at least one capillary tube into a storage unit by disrupting a surface tension of the blood drop, and
a vacuum connector communicated with the channel, extended outwardly from the collection unit, and connected to a pressure control unit to remove air from the channel and create an alternating negative pressure in the channel; and
the storage unit disposed under the collection unit.
2. The device of claim 1 , further comprising a pad disposed on the top surface of the collection unit.
3. The device of claim 1 , wherein the collection unit further comprises a funnel structure surrounding the at least one capillary tube.
4. The device of claim 1 , wherein the collection unit further comprises at least one holder holding the at least one capillary tube.
5. The device of claim 1 , wherein the at least one capillary tube is replaced with multiple capillary tubes to form a bunch of capillary tubes.
6. The device of claim 1 , wherein the vacuum connector comprises a partition plate inside the collection unit and extended toward the storage unit.
7. The device of claim 1 , wherein the collection unit further comprises a venting connector communicated with the channel and connected to the pressure control unit to create the alternating negative pressure in the channel.
8. The device of claim 1 , wherein the storage unit comprising a tube, a tank, a vessel, a syringe-like storage unit, an analogue, or any combination thereof is detachable from the collection unit for delivering the blood sample.
9. The device of claim 1 , wherein the storage unit comprising a storage channel, a storage well, an absorbent material, an analogue, or any combination thereof is non-detachable from the collection unit.
10. A system for collecting a blood sample, comprising:
a cartridge comprising the collection unit and the storage unit according to claim 1 ; and
a docking station comprising a pressure control unit.
11. The system of claim 10 , wherein the cartridge is removable from the system.
12. The system of claim 10 , wherein the collection unit further comprises a puncturing mechanism adjacent to the top window of the collection unit.
13. The system of claim 10 , further comprising a pad disposed on the top surface of the collection unit.
14. The system of claim 10 , wherein the collection unit further comprises a funnel structure surrounding the at least one capillary tube.
15. The system of claim 10 , wherein the at least one capillary tube is replaced with multiple capillary tubes to form a bunch of capillary tubes.
16. The system of claim 10 , wherein the vacuum connector comprises a partition plate inside the collection unit and extended toward the storage unit.
17. The system of claim 10 , wherein the collection unit further comprises a venting connector communicated with the channel and connected to the pressure control unit to create the alternating negative pressure in the channel.
18. The system of claim 10 , wherein the storage unit comprising a tube, a tank, a vessel, a syringe-like storage unit, an analogue, or any combination thereof is detachable from the collection unit for delivering the blood sample.
19. The system of claim 10 , wherein the storage unit comprising a storage channel, a storage well, an absorbent material, an analogue, or any combination thereof is non-detachable from the collection unit.
20. The system of claim 10 , further comprising at least one sensor configured to detect a volume of the blood sample.
21. The system of claim 10 , further comprising a compression unit disposed above the collection unit for compressing a finger of a user.
22. A method of collecting a blood sample, comprising:
providing a collection unit having a top window, a top surface, and a channel communicated with the top window;
providing at least one capillary tube in the collection unit having a top end adjacent to the top window for guiding a blood drop from the puncture to flow inside or along the at least one capillary tube, wherein a distance between the top end of the at least one capillary tube and the top surface of the collection unit is in a range of 1.0 mm to 5.0 mm, such that the top end of the at least one capillary tube is used to contact with a blood drop from a puncture to continuously draw the blood flowing inside or along the at least one capillary tube into a storage unit by disrupting a surface tension of the blood drop;
removing air from the channel through a vacuum connector to create an alternating negative pressure in the channel by connecting the channel and a pressure control unit, wherein the vacuum connector is communicated with the channel and is extended outwardly from the collection unit; and
storing the blood sample in the storage unit disposed underneath the collection unit.
23. The method of claim 22 , further comprising providing a pad on the top surface of the collection unit for a tight contact or warming a puncture site.
24. The method of claim 22 , wherein the negative pressure is in a range of −10 kPa to −80 kPa.
25. The method of claim 22 , wherein the alternating negative pressure is created in the channel by connecting the channel and the pressure control unit via a venting connector.
26. The method of claim 22 , further comprising collecting a specific volume of the blood sample using at least one sensor in conjunction with controlling the negative pressure in the channel.
27. The method of claim 22 , further comprising squeezing a fingertip of a user with a compression unit disposed above the collection unit to obtain the blood sample from the puncture.