IP Library Granted Patent US 10,463,778
Granted Patent B2
US 10,463,778 · App. 15/167,368 · Granted Nov 5, 2019

Blood treatment machine having electrical heartbeat analysis

Inventors: Rodolfo Roger (Clearwater, FL); Robert Childers (Trinity, FL); Thomas D. Kelly (Highland Park, IL)
Assignees: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE S.A.
A61M1/3656A61N1/00A61M2205/17A61M2205/18A61M2205/3317A61M2205/3375A61M2205/3584A61M2205/52A61M2230/005A61M2230/04A61M2230/40
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Quick Facts
Patent No.
US 10,463,778
App. No.
15/167,368
Granted
Nov 5, 2019
Kind
B2
Abstract

A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump; a venous line; and a heartbeat evaluation system including (i) a first electrode coupled to the arterial line or to a patient, (ii) a second electrode coupled to the venous line, (iii) electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and (iv) signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume.

Claims (52)

1. A blood treatment machine comprising:

a blood pump;

an arterial line in fluid communication with the blood pump;

a venous line; and

a heartbeat evaluation system including

(i) a first electrode coupled to the arterial line or to a patient,

(ii) a second electrode coupled to the venous line,

(iii) electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and

(iv) signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume.

2. The blood treatment machine of claim 1 , which is further configured to determine a change in the electrical heartbeat signal sufficient to expect that an access disconnection of the venous line has occurred.

3. The blood treatment machine of claim 2 , wherein the determined change sufficient to expect that an access disconnection of the venous line has occurred is a loss of the heartbeat signal.

4. The blood treatment machine of claim 2 , wherein the electronic circuitry is split into a first branch in communication with the signal processing for calculating the at least one of (a) to (e) and a second branch for determining that a change in the electrical heartbeat signal sufficient to expect that an access disconnection of the venous line has occurred.

5. The blood treatment machine of claim 1 , wherein the signal processing includes at least one of a random access memory (“RAM”) or digital signal processing (“DSP”).

6. The blood treatment machine of claim 1 , wherein the electronic circuitry includes signal conditioning circuitry.

7. The blood treatment machine of claim 1 , wherein at least one of the first electrode or the second electrode is coupled to the respective arterial line or the venous line, respectively, via a direct contact, a capacitive coupling or an inductive coupling.

8. The blood treatment machine of claim 1 , wherein the sensed heartbeat signal is translated into an electrocardiogram for further processing.

9. The blood treatment machine of claim 8 , wherein the electrocardiogram is used to determine a parameter useful when performing a blood treatment.

10. A blood treatment machine comprising:

a blood pump;

an arterial line in fluid communication with the blood pump;

a venous line; and

a heartbeat evaluation system including

(i) a first electrode coupled to the arterial line or to a patient,

(ii) a second electrode coupled to the venous line, and

(iii) electronic circuitry and signal processing cooperating to communicate electrically with the first electrode and the second electrode, generate an electrocardiogram from the electrical heartbeat signal, and derive at least one of (a) an enlargement of the patient's heart (b) an insufficient blood flow to the patient, (c) an injury to the patient's heart, (d) problems with the patient's heart rhythm, (e) changes in electrical activities of the patient's heart, or (f) inflammation of the sac surrounding the patient's heart.

11. The blood treatment machine of claim 10 , wherein the at least one of (a) to (f) is used to determine a parameter useful when performing a blood treatment.

12. The blood treatment machine of claim 10 , which is further configured to determine a change in the electrical heartbeat signal sufficient to expect that an access disconnection of the venous line has occurred.

13. The blood treatment machine of claim 12 , wherein the electronic circuitry is split into a first branch in communication with the signal processing for deriving the at least one of (a) to (f) and a second branch for determining that a change in the electrical heartbeat signal sufficient to expect that an access disconnection of the venous line has occurred.

14. The blood treatment machine of claim 10 , wherein the signal processing includes at least one of a random access memory (“RAM”) or digital signal processing (“DSP”).

15. The blood treatment machine of claim 10 , wherein the electronic circuitry includes signal conditioning circuitry.

16. A blood treatment machine comprising:

a blood pump;

a cardiac catheter assembly in fluid communication with the blood pump and structured for insertion into a patient's (i) vein, (ii) artery, (iii) graft, or (iv) heart, the cardiac catheter assembly including a first electrode, and a second electrode;

electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient; and

signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume.

17. The blood treatment machine of claim 16 , wherein the cardiac catheter assembly includes an arterial access section operable with the blood pump.

18. A blood treatment machine comprising:

a blood pump;

a cardiac catheter assembly in fluid communication with the blood pump and structured for insertion into a patient's (i) vein, (ii) artery, (iii) graft, or (iv) heart, the cardiac catheter assembly including a first electrode, and a second electrode; and

electronic circuitry and signal processing cooperating to communicate electrically with the first electrode and the second electrode, generate an electrocardiogram from the electrical heartbeat signal, and derive at least one of (a) an enlargement of the patient's heart (b) an insufficient blood flow to the patient, (c) an injury to the patient's heart, (d) problems with the patient's heart rhythm, (e) changes in electrical activities of the patient's heart, or (f) inflammation of the sac surrounding the patient's heart.

19. The blood treatment machine of claim 18 , wherein the cardiac catheter assembly includes an arterial access section operable with the blood pump.

20. A blood treatment machine comprising:

a blood pump;

an arterial line in fluid communication with the blood pump;

a venous line;

a first electrode coupled to (i) the arterial line, (ii) a patient, or (iii) a cardiac catheter assembly;

a second electrode coupled to (i) the venous line, or (ii) the cardiac catheter assembly; and

electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and

signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume

or

electronic circuitry and signal processing cooperating to communicate electrically with the first electrode and the second electrode, generate an electrocardiogram from the electrical heartbeat signal, and derive at least one of (a) an enlargement of the patient's heart (b) an insufficient blood flow to the patient, (c) an injury to the patient's heart, (d) problems with the patient's heart rhythm, (e) changes in electrical activities of the patient's heart, or (f) inflammation of the sac surrounding the patient's heart.

21. The blood treatment machine of claim 20 , wherein the arterial and venous lines are sections of the cardiac catheter assembly.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER HEALTHCARE SA
To: VANTIVE HEALTH GMBH
Reel/Frame 073433/0234 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER INTERNATIONAL INC.
To: VANTIVE US HEALTHCARE LLC
Reel/Frame 074046/0877 →
SECURITY INTEREST Recorded Jan 31, 2025
From: VANTIVE US HEALTHCARE LLC; GAMBRO RENAL PRODUCTS, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 070076/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 2, 2016
From: ROGER, RODOLFO G.; CHILDERS, ROBERT W.; KELLY, THOMAS D.
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE S.A.
Reel/Frame 038783/0663 →
Continuity (5)
Continuation 14551965 · Nov 24, 2014
Continuation 13400468 · Feb 20, 2012
Continuation 11673390 · Feb 9, 2007
Related Publication 20170340801A1 · Nov 30, 2017
Related Publication 20180185564A9 · Jul 5, 2018
Cited By (1)
US 12,415,057