Intraocular implants and methods and kits therefor
Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and maintains the patency of the canal without substantially interfering with transmural fluid flow across the canal. The devices utilize the natural drainage process of the eye and can be implanted with minimal trauma to the eye. Kits include a support and an introducer for implanting the support within Schlemm's canal. Methods include implanting a support within Schlemm's canal, wherein the support is capable of maintaining the patency of the canal without substantial interference with transmural fluid flow across the canal.
1. A method for treating an eye condition, comprising:
implanting a support within Schlemm's canal, wherein the support comprises an arcuate member, wherein at least a portion of the arcuate member has a radius of curvature smaller than the radius of curvature of Schlemm's canal such that at least a portion of the arcuate member extends out of Schlemm's canal.
2. The method of claim 1 , wherein the support has at least one fenestration.
3. The method of claim 1 , wherein the support has a length equal to about a quarter or less than a quarter of the circumference of Schlemm's canal.
4. The method of claim 1 , wherein at least a portion of the support is made from a biocompatible polymer.
5. The method of claim 4 , wherein the biocompatible polymer comprises a biodegradable polymer.
6. The method of claim 1 , wherein at least a portion of the support is made from a shape memory material.
7. The method of claim 6 , wherein the shape memory material comprises a shape memory alloy.
8. The method of claim 7 , wherein the shape memory alloy comprises a nickel titanium alloy.
9. The method of claim 1 , wherein at least a portion of the support is made from a biocompatible metal.
10. The method of claim 9 , wherein the metal is titanium.
11. The method of claim 1 , wherein at least a portion of the support is hollow.
12. The method of claim 1 , wherein at least a portion of the support is porous.
13. The method of claim 1 , wherein when the support is disposed within a cylindrical section of the lumen of Schlemm's canal having an internal wall surface area C, the support contacts less than 30% of C.
14. The method of claim 1 , wherein when the support is disposed within a cylindrical section of the lumen of Schlemm's canal having an internal wall surface area C, the support contacts less than 10% of C.
15. The method of claim 1 , wherein the support is flexible.
16. The method of claim 1 , wherein the support is rigid.
17. The method of claim 1 , wherein the support does not substantially interfere with longitudinal flow along Schlemm's canal.
18. The method of claim 1 , wherein the support does not substantially interfere with transmural flow into and out of Schlemm's canal.
19. The method of claim 1 , further comprising preloading the support into an introducer and delivering the support from the introducer into Schlemm's canal.
20. The method of claim 19 , wherein the support is delivered from the introducer using a pusher.