IP Library Granted Patent US 10,596,235
Granted Patent B2
US 10,596,235 · App. 15/182,779 · Granted Mar 24, 2020

Pharmaceutical preparation

Inventors: Christian Rämsch (Groß Norende, DE); Manfred Kurfürst (Moorrege, DE); Rainer Friedel (Hannover, DE); Olaf Friedrich (Tornesch, DE); Silke Hüttler (Altenmoor, DE)
Assignee: Nordmark Arzneimittel GmbH & Co. KG
A61K38/465
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Quick Facts
Patent No.
US 10,596,235
App. No.
15/182,779
Granted
Mar 24, 2020
Kind
B2
Abstract

The pharmaceutical preparation for the treatment of pancreatic insufficiency comprises a liquid administering form of enzymes.

Claims (10)

1. A method for the treatment of pancreatic insufficiency comprising the steps of:

providing a pharmaceutical composition consisting of water and a bacterial lipase, and which has been stored for at least one week, and

administering the pharmaceutical composition to a patient suspected of pancreatic insufficiency.

2. The method according to claim 1 , wherein the pancreatic insufficiency is mucoviscidosis or pancreatitis.

3. The method according to claim 1 , wherein the pharmaceutical composition is prepared by

a) direct fabrication of the lipase as liquid solution or

b) dissolution of the active constituent lipase in water.

4. The method according to claim 1 , whereby the bacterial lipase is selected from the group consisting of the Burkholderia type lipase, Pseudomonas type lipase, and Burkholderia plantarii type lipase.

5. The method of claim 1 , wherein the bacterial lipase is active to a pH as low as 3.

6. The method according to claim 1 , wherein the bacterial lipase is of the Burkholderia plantarii type lipase.

Assignments (5)
CHANGE OF NAME Recorded Sep 28, 2021
From: NORDMARK ARZNEIMITTEL GMBH & CO. KG
To: NORDMARK ARZNEIMITTEL HOLDING GMBH & CO. KG
Reel/Frame 057630/0614 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 15, 2021
From: NORDMARK ARZNEIMITTEL HOLDING GMBH & CO. KG
To: NORDMARK PHARMA GMBH
Reel/Frame 057484/0363 →
CHANGE OF NAME Recorded Sep 15, 2021
From: NORDMARK ARZNEIMITTEL GMBH & CO. KG
To: NORDMARK ARZNEIMITTEL HOLDING GMBH & CO. KG
Reel/Frame 057517/0496 →
CHANGE OF NAME Recorded Sep 13, 2021
From: ORDMARK ARZNEIMITTEL HOLDING GMBH & CO. KG
To: NORDMARK PHARMA GMBH
Reel/Frame 057584/0374 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2016
From: RAMSCH, CHRISTIAN; KURFURST, MANFRED; FRIEDEL, RAINER; FRIEDRICH, OLAF; HUTTLER, SILKE
To: NORDMARK ARZNEIMITTEL GMBH & CO. KG
Reel/Frame 038917/0100 →
Continuity (2)
Continuation 13146653
Related Publication 20160287679A1 · Oct 6, 2016