Filtration system for preparation of fluids for medical applications
Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed through a first filtration step which is effective for creating purified water and a pair of ultrafilters placed at the outlet. The ultrafilters are separated by an intervening flow path to prevent grow-through from the outlet end upstream. In embodiments, a recirculation path with an air removing filter helps to eliminate air from the ultimate product water.
1. A method of performing a medical treatment, comprising:
at a time prior to a dialysis treatment, pumping water into a water purification device, including a disposable filter module that includes deionization filters, to generate product water having a resistivity of at least 2 megohms;
passing the product water from said pumping through a resistivity monitor configured to shut down said pumping when a measured resistivity falls below said 2 megohms;
fluidly coupling a disposable batch container to receive the product water;
combining said product water with a concentrate from a concentrate container for holding the concentrate to produce a mixture in the disposable batch container that is empty before the fluidly coupling and is preattached to the concentrate container, the concentrate container and the batch container being sterilized together as one consumable unit;
measuring a conductivity of said mixture in said batch container using a conductivity sensor permanently attached to said batch container; and
pumping said mixture from said batch container to administer the dialysis treatment.
2. The method of claim 1 , wherein the concentrate container and the batch container are interconnected by tubing containing a sterile filter.
3. The method of claim 1 , further comprising sterile-filtering said product water prior to said combining.
4. The method of claim 1 , wherein the measuring includes drawing a sample of said mixture over the conductivity sensor.
5. The method of claim 4 , wherein the conductivity sensor is attached to a fluid port of said batch container.
6. The method of claim 1 , wherein the concentrate container includes a burstable sealed membrane.
7. The method of claim 1 , wherein the concentrate container is connected by tubing to said batch container.
8. The method of claim 2 , further comprising sterile-filtering said product water prior to said combining.
9. The method of claim 2 , wherein the measuring includes drawing a sample of said mixture over the conductivity sensor.
10. The method of claim 2 , wherein the concentrate container includes a burstable sealed membrane.
11. The method of claim 2 , wherein the concentrate container is connected by tubing to said batch container.
12. The method according to claim 1 , wherein
said concentrate is a concentrated dialysate liquid,
said concentrate container is filled with the concentrated dialysate liquid, and
said mixture is a dialysate mixture.
13. The method according to claim 2 , wherein
said concentrate is a concentrated dialysate liquid,
said concentrate container is filled with the concentrated dialysate liquid, and
said mixture is a dialysate mixture.
14. The method according to claim 8 , wherein
said concentrate is a concentrated dialysate liquid,
said concentrate container is filled with the concentrated dialysate liquid, and
said mixture is a dialysate mixture.
15. The method according to claim 11 , wherein
said concentrate is a concentrated dialysate liquid,
said concentrate container is filled with the concentrated dialysate liquid, and
said mixture is a dialysate mixture.
16. The method according to claim 1 , wherein
the conductivity sensor protrudes into the batch container through a wall of the batch container.
17. The method according to claim 11 , wherein
the conductivity sensor protrudes into the batch container through a wall of the batch container.