APPARATUS, SYSTEMS AND METHODS FOR DETERMINING TISSUE OXYGENATION
A surgical instrument may be configured to sense a light re-emitting probe to resolve tissue oxygenation, the surgical instrument including: an optical emitter configured to excite the light re-emitting probe within an absorption band of the light re-emitting probe; an optical detector configured to receive the re-emitted light from the probe; and a signal processor configured to resolve the tissue oxygenation based on the received light. The surgical instrument can be a surgical stapler anvil or a flexible substrate having a tissue interfacing surface. Further, a monitoring device may be configured to map oxygenation of a tissue containing a light re-emitting probe, the monitoring device including: an optical emitter configured to excite the light re-emitting probe; at least one optical detector configured to receive the re-emitted light from the probe; and a signal processor that is configured to resolve the tissue oxygenation at multiple points to generate an oxygen map.
1 . A surgical instrument configured to sense a light re-emitting probe to resolve tissue oxygenation, the surgical instrument comprising:
at least one optical emitter that is configured to excite the light re-emitting probe within an absorption band of the light re-emitting probe;
at least one optical detector configured to receive the re-emitted light from the probe; and
a signal processor that is configured to resolve the tissue oxygenation based on the received light.
2 . The surgical instrument according to claim 1 , further comprising an applicator configured to provide a target tissue with a medium, the medium containing the light re-emitting probe.
3 . The surgical instrument according to claim 1 , wherein the signal processor is configured to resolve the tissue oxygenation based on a lifetime of the re-emitted light.
4 . The surgical instrument according to claim 1 , wherein the surgical instrument is a surgical stapler anvil.
5 . The surgical instrument according to claim 2 , wherein the applicator is at least one injector that is configured to inject the medium into the target tissue.
6 . The surgical instrument according to claim 1 , further comprising an interrogator instrument that is configured to interrogate the tissue.
7 . The surgical instrument according to claim 1 , wherein the surgical instrument is a flexible substrate having a tissue interfacing surface.
8 . The surgical instrument according to claim 1 , wherein the signal processor makes a determination of an operation success based on the resolution of the tissue oxygenation.
9 . The surgical instrument according to claim 1 , further comprising a temperature sensor that is configured to detect a temperature of the tissue.
10 . The surgical instrument according to claim 1 , further comprising at least one sensor configured to monitor interaction forces of at least one of compression pressure and tissue tension of the tissue.
11 . The surgical instrument according to claim 1 , wherein the probe is a phosphorescent probe that has multiple absorption wavelengths.
12 . The surgical instrument according to claim 1 , wherein the surgical instrument is communicatively coupled to a base station.
13 . A surgical stapler anvil configured to sense a light re-emitting probe to resolve tissue oxygenation, the surgical stapler anvil comprising:
at least one optical emitter that is configured to excite the light re-emitting probe;
at least one optical detector that is configured to receive the re-emitted light from the probe; and
a signal processor that is configured to resolve the tissue oxygenation based on the received light.
14 . The surgical stapler anvil according to claim 13 , wherein the surgical stapler anvil is communicatively coupled to a base station.
15 . The surgical stapler anvil according to claim 13 , wherein the signal processor makes a determination of an operation success based on the resolution of the tissue oxygenation.
16 . The surgical stapler anvil according to claim 13 , further comprising a temperature sensor that is configured to detect a temperature of the tissue.
17 . The surgical stapler anvil according to claim 13 , further comprising at least one sensor configured to monitor interaction forces of at least one of compression pressure and tissue tension of the tissue.
18 . A monitoring device configured to sense a light re-emitting probe to resolve tissue oxygenation, the monitoring device comprising:
a flexible substrate having a tissue interfacing surface, the tissue interfacing surface containing (1) at least one optical emitter that is configured to excite the light re-emitting probe; and (2) at least one optical detector configured to receive the re-emitted light from the probe; and
a signal processor that is configured to resolve the tissue oxygenation based on the received light.
19 . The monitoring device according to claim 18 , wherein the monitoring device comprises at least one injector configured to inject a medium into target tissue, the medium containing the light re-emitting probe.
20 . The monitoring device according to claim 18 , wherein the monitoring device is communicatively coupled to a base station.
21 . The monitoring device according to claim 18 , wherein the signal processor makes a determination of an operation success based on the resolution of the tissue oxygenation.
22 . The monitoring device according to claim 18 , further comprising a temperature sensor that is configured to detect a temperature of the tissue.
23 . The monitoring device according to claim 18 , wherein the flexible substrate is configured to be one or more of: (1) affixed to skin and (2) affixed to an internal tissue.
24 . The monitoring device according to claim 18 , wherein the monitoring device is at least partially bioabsorbable.
25 . A monitoring device configured to map oxygenation of a tissue containing a light re-emitting probe, the monitoring device comprising:
at least one optical emitter that is configured to excite the light re-emitting probe;
at least one optical detector configured to receive the re-emitted light from the probe; and
a signal processor that is configured to resolve the tissue oxygenation at multiple points to generate an oxygen map.
26 . The monitoring device according to claim 25 , further comprising at least one injector configured to inject a medium into target tissue, the medium containing the light re-emitting probe.
27 . The monitoring device according to claim 25 , further comprising a temperature sensor that is configured to detect a temperature of the tissue.
28 . The monitoring device according to claim 25 , wherein the optical detector is at least one of a CCD array, a CMOS image sensor and a camera.
29 . The monitoring device according to claim 25 , wherein the monitoring device is an endoscopic instrument.
30 . The monitoring device according to claim 25 , wherein the monitoring device is ingestible.