IP Library Granted Patent US 10,671,704
Granted Patent B2
US 10,671,704 · App. 15/215,465 · Granted Jun 2, 2020

Predicting immune response

Inventors: Timothy Webb (Concord, CA); Jesse Cotari (San Francisco, CA); Justin Rebo (Crockett, CA); Stuart Alexander Jacobson (San Francisco, CA)
Assignee: PRIOBIO, LLC
G06F19/3418A61B5/0022A61B5/021A61B5/024A61B5/02055A61B5/0531A61B5/1113A61B5/1118A61B5/14542A61B5/15A61B5/150022A61B5/150305A61B5/150343A61B5/150351A61B5/41A61B5/486A61B5/7275A61B5/7475G09B5/125G09B7/02A61B5/150099A61B5/15105A61B5/15113A61B5/15117A61B5/15142A61B5/150251A61B5/150412A61B5/150755A61B5/7264A61B2503/10A61B2505/09
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Quick Facts
Patent No.
US 10,671,704
App. No.
15/215,465
Granted
Jun 2, 2020
Kind
B2
Abstract

Systems, methods, and non-transitory computer-readable storage media for gathering activity data describing a user's activities from one or more activity sensors and using the activity data to predict immune-response to the activity. Predicting immune-response can involve creating, personalizing, and refining immune-response prediction models based on demographic user data, activity data, blood sample data, personal genetic information.

Claims (26)

1. An apparatus comprising:

a display associated with a user input;

an activity sensor coupled with a processor, a communication interface, and a memory storing instructions that, when executed by the processor, cause the apparatus to:

receive, through the user input, self-reported user information;

create, based on the self-reported user information, a recommended baseline activity regimen for achieving at least one immunity-related goal, the at least one immunity-related goal comprising one or more of immune cell or progenitor mobilization, altering circulation rates of one of immune cells or progenitors, changes in absolute or relative abundance of immune cell types in circulation, alterations in one of abundance or localization of immune cell proteins, changes in RNA expression, or alterations of immune cell structure;

display the recommended baseline activity regimen;

receive activity data for the user from the activity sensor, the activity data including one or more of heart rate, acceleration, blood pressure, external temperature, body temperature, geographical location, pressure, skin conductance, blood oxygen level, or glucose level;

determine, by providing the activity data to an immune-response prediction model, when the activity data indicates a user activity that deviates from the recommended baseline activity regimen to a predetermined threshold degree; and

provide feedback to the user for correcting the deviation from the recommended baseline activity regimen; and

a blood collection kit containing a blood collection apparatus and a blood preservation and storage unit, the blood collection kit configured to collect a user's blood after performing the recommended baseline activity regimen and send the collected blood sample to a blood analysis entity; wherein the communication interface is further configured to receive, from a network location associated with the blood analysis entity, a set of blood analysis results; and wherein the instructions further cause the apparatus to update the recommended baseline activity regimen using the blood analysis results.

2. The apparatus of claim 1 , wherein the instructions further cause the apparatus to:

receive, from the user through the user input, a user authorization for access to user blood sample data from a network location;

retrieve, using the communication interface, blood sample data from the network location; and

update the recommended baseline activity regimen based on the blood sample data.

3. The apparatus of claim 2 , wherein the instructions further cause the apparatus to personalize the recommended baseline activity regimen based on the blood sample data to create an updated activity regimen that increases the mobilization of one or more specific blood cells.

4. The apparatus of claim 2 , wherein the blood sample data comprises data for multiple blood draws performed over a period of time, and wherein the instructions further cause the apparatus to update the recommended baseline activity regimen based on the blood sample data to create an updated activity regimen that increases a mobilization stacking effect on blood cell mobilization.

5. The apparatus of claim 1 , wherein the instructions further cause the apparatus to create a recommended baseline activity regimen for achieving at least one immunity-related goal by inputting the self-reported user information into mobilization prediction model stored in the memory.

6. The apparatus of claim 1 , wherein the instructions further cause the communication interface to:

transmit the self-reported user information to a network location containing a program for creating a recommended baseline activity regimen for achieving at least one immunity-related goal by inputting the self-reported user information into a mobilization prediction model; and

receive the recommended baseline activity regimen from the network location.

7. The apparatus of claim 1 , wherein the instructions further cause the apparatus to display, as part of the recommended baseline activity regimen, one or more of an activity type, an exertion intensity and an exertion duration.

8. The apparatus of claim 1 , wherein the activity sensor comprises one or more of a heart rate monitor, an accelerometer, a blood pressure monitor, an external temperature monitor, a body temperature monitor, a location tracking system, a pressure sensor, a skin conductance sensor, and a blood oxygen level sensor.

9. The apparatus of claim 1 , wherein the instructions further cause the apparatus to:

display an interface element that allows a user to request to access, though the communication interface, personal genetic information from a network location; and

receive, through the communication interface, personal genetic information from a network location;

wherein the self-reported user information includes the personal genetic information including one or more of simple nucleotide polymorphism data and full genetic sequencing data.

Assignments (3)
CORRECTION OF COVER SHEET ERROR TO CORRECT THE SPELLING OF THE RECEIVING PARTY DATA TO REMOVE THE COMMA BEFORE LLC PREVIOUSLY RECORDED ON REEL 053246, FRAME 0663. RECEIVING PARTY CONFIRMS IT IS TRANSFUSION HEALTH LLC. Recorded Aug 3, 2020
From: PRIOBIO, LLC
To: TRANSFUSION HEALTH LLC
Reel/Frame 053387/0424 →
CHANGE OF NAME Recorded Jul 17, 2020
From: PRIOBIO, LLC
To: TRANSFUSION HEALTH, LLC
Reel/Frame 053246/0663 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2016
From: WEBB, TIMOTHY; COTARI, JESSE; REBO, JUSTIN; JACOBSON, STUART ALEXANDER
To: PRIOBIO, LLC
Reel/Frame 039275/0008 →
Continuity (2)
Provisional Application 62195837 · Jul 23, 2015
Related Publication 20170024536A1 · Jan 26, 2017