IP Library › Granted Patent US 10,368,532
Granted Patent B2
US 10,368,532 · App. 15/224,336 · Granted Aug 6, 2019

Transition cow index

Inventors: Katrina Dattilo (DeForest, WI); Yalda Zare (DeForest, WI); Gabriela Carolina Marquez Betz (DeForest, WI); Kaleena Stephan (DeForest, WI); Ryan Starkenburg (DeForest, WI); Cristian Vergara (DeForest, WI)
Assignee: Genus, PLC
A01K67/02A61D19/04G16B20/00A01K2227/101
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Quick Facts
Patent No.
US 10,368,532
App. No.
15/224,336
Granted
Aug 6, 2019
Kind
B2
Abstract

Applicants have identified that three critical phenotypic/genetic measures are highly correlated with transition period health and may be used in selection and breeding protocols and/or in combination with traditional breeding and marker assisted selection methods to improve predictability of transition period health. According to the invention genetic evaluations for mastitis, ketosis, and metritis have been found to be highly predictive of overall transition health. The genetic evaluations are produced by directly measuring thousands of clinical cases of mastitis, ketosis, and metritis in ancestors of a particular animal and using this data in selection. Applicant's selection criteria can quickly impact a breeders population by reducing transition cow disease incidence in the initial population and in progeny.

Claims (22)

1. A method of breeding bovine animals to create a progeny population with improved milk production traits comprising:

a) assaying the lineage of one or more bovine animals for mastitis, metritis, and ketosis incidence in one or more ancestors of said bovine animal, wherein said metritis, mastitis, and ketosis incidence is assigned an estimated breeding value;

b) selecting a bovine animal from step a) with a favorable said estimated breeding value, wherein the selected bovine animal is used as a first parent bovine animal; and

c) breeding said first parent bovine animal with a second parent bovine animal to create said progeny population, wherein female bovine animals of said progeny population demonstrate improved milk production and health during the transition period when compared to female bovine animals of a progeny population where a first parent bovine animal has not been so selected.

2. The method of claim 1 , wherein said first parent bovine animal is a cow.

3. The method of claim 1 , wherein said first parent bovine animal is a sire.

4. The method of claim 1 , wherein both the first parent bovine animal and the second parent bovine animal are selected based on favorable said estimated breeding value.

5. The method of claim 1 , wherein said mastitis, metritis, and ketosis incidence data is collected for multiple animals from multiple locations.

6. The method of claim 1 , wherein said ancestors include thousands of animals.

7. The method of claim 1 , wherein said first parent bovine animal is ranked within the top 10% of bovine animals based on said estimated breeding value.

8. The method of claim 1 , wherein said first parent bovine animal is ranked within the top 20% of bovine animals based on said estimated breeding value.

9. The method of claim 1 , wherein said first parent bovine animal is ranked within the top 30% of bovine animals based on said estimated breeding value.

10. The method of claim 1 , wherein said estimated breeding value is combined with estimated breeding values for milk, fat, and protein yield, fat and protein percentage, productive life, and/or somatic cell scores to determine a favorable combination of the same.

11. A method for selectively breeding bovine animals using a multiple ovulation and embryo transfer procedure (MOET) procedure, the method comprising:

superovulating a first female bovine animal selected according to the method of claim 1 , collecting eggs from said superovulated first female bovine animal,

in vitro fertilizing said collected eggs from a suitable male bovine animal, implanting said fertilized eggs into a second female bovine animal and

allowing for an embryo to develop from said implanted fertilized egg to create a population of male and female bovine progeny animals, wherein said female bovine progeny animals have improved milk production and health, during the transition period when compared to a female bovine animal of a progeny population where the first female bovine animal has not been so selected.

12. The method of claim 1 , wherein said breeding comprises:

collecting semen from said first parent bovine animal; and

using said semen for fertilizing said second parent bovine animal.

13. The method according to claim 12 , wherein the second parent bovine animal is in-vitro fertilized.

14. The method according to claim 12 , wherein a Multiple Ovulation and Embryo Transfer (MOET) procedure is used.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 20, 2021
From: GENUS PLC
To: ABS GLOBAL, INC.
Reel/Frame 055975/0885 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 5, 2016
From: DATTILO, KATRINA; ZARE, YALDA; MARQUEZ-BETZ, GABRIELA; STEPHAN, KALEENA; STARKENBURG, RYAN; VERGARA, CRISTIAN
To: GENUS, PLC
Reel/Frame 040231/0176 →
Continuity (3)
Provisional Application 62350813 · Jun 16, 2016
Provisional Application 62198455 · Jul 9, 2015
Related Publication 20170360012A1 · Dec 21, 2017