IP Library › Granted Patent US 10,301,329
Granted Patent B2
US 10,301,329 · App. 15/227,112 · Granted May 28, 2019

Boron-containing small molecules as antiprotozoal agents

Inventors: Daitao Chen (Raleigh, NC); Matthew Orr (Raleigh, NC); Jessica Sligar (Cary, NC); Robert Jacobs (Wake Forest, NC); Jacob J. Plattner (Berkeley, CA)
Assignee: Anacor Pharmaceuticals, Inc.
C07F5/025A01N55/08A61K31/69
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Quick Facts
Patent No.
US 10,301,329
App. No.
15/227,112
Granted
May 28, 2019
Kind
B2
Abstract

This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Claims (2)

1. A method of killing and/or preventing the growth of Trypanosoma brucei brucei, comprising: contacting the Trypanosoma brucei brucei with an effective amount of a compound having a structure according to the following formula:

or a pharmaceutically acceptable salt thereof, thereby killing and/or preventing the growth of the Trypanosoma brucei brucei.

Assignments (2)
CHANGE OF NAME Recorded Jan 11, 2024
From: ANACOR PHARMACEUTICALS, INC.
To: ANACOR PHARMACEUTICALS, LLC
Reel/Frame 066285/0860 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2016
From: CHEN, DAITAO; ORR, MATTHEW; SLIGAR, JESSICA; JACOBS, ROBERT; PLATTNER, JACOB J.
To: ANACOR PHARMACEUTICALS, INC.
Reel/Frame 039330/0147 →
Continuity (4)
Division 12852351 · Aug 6, 2010
Provisional Application 61234213 · Aug 14, 2009
Provisional Application 61315774 · Mar 19, 2010
Related Publication 20160340369A1 · Nov 24, 2016