IP Library › Granted Patent US 9,570,278
Granted Patent B2
US 9,570,278 · App. 15/227,449 · Granted Feb 14, 2017

Coupling device for mass spectrometry apparatus

Inventors: Kazumasa Kinoshita (Fujisawa, JP); Yuki Kudo (Fujisawa, JP); Takao Nishiguchi (Fujisawa, JP)
Assignee: BIOCHROMATO, INC.
H01J49/0422H01J49/0027
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Quick Facts
Patent No.
US 9,570,278
App. No.
15/227,449
Granted
Feb 14, 2017
Kind
B2
Abstract

An object of the present invention is to provide a technology that enables highly sensitive atmospheric-pressure real-time mass spectrometry of a volatile substance. The present invention provides a coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device including (A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port, (B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication, and (C) a space for mixing excitation gas and sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication.

Claims (15)

1. A coupling device for a mass spectrometry apparatus that is an interface member to be connected to an atmospheric-pressure real-time mass spectrometry apparatus, the coupling device comprising:

(A) an excitation gas introducing port, a sample gas introducing port, and an ionized sample gas discharging port;

(B) a channel through which the excitation gas introducing port and the ionized sample gas discharging port are in communication;

(C) a space for mixing an excitation gas and a sample gas being formed in a region of a portion of the channel recited in (B), by the coupling device having a structure in which the sample gas introducing port and the channel recited in (B) are in communication; and

(D) an outside air introducing port, and having a structure in which a channel from the outside air introducing port is in communication with the channel recited in (B).

2. The coupling device for a mass spectrometry apparatus according to claim 1 ,

wherein the coupling device is an interface member for being connected between an excitation gas ejecting port of an ion source using a principle of a DART method and an ionized sample gas collecting port of a mass spectrometer.

3. The coupling device for a mass spectrometry apparatus according to claim 1 ,

wherein the space recited in (C) is a space formed in a channel portion having a linear-tube shape in the channel recited in (B).

4. The coupling device for a mass spectrometry apparatus according to claim 1 ,

wherein the space recited in (C) is a space formed such that a cross-sectional area of the channel recited in (B) on the excitation gas introducing port side is relatively large compared with the channel on the ionized sample gas discharging port side.

5. The coupling device for a mass spectrometry apparatus according to claim 1 ,

which has a structure in which the channel extending from the outside air introducing port recited in (D) is in communication with the channel recited in (B) at a position on the ionized sample gas discharging port side with respect to the space recited in (C).

6. An atmospheric-pressure real-time mass spectrometry apparatus provided with the coupling device for a mass spectrometry apparatus according to claim 1 .

7. A mass spectrometry method for performing mass spectrometry of a volatile substance in real time under ambient conditions, which uses the atmospheric-pressure real-time mass spectrometry apparatus according to claim 6 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2016
From: KINOSHITA, KAZUMASA; KUDO, YUKI; NISHIGUCHI, TAKAO
To: BIOCHROMATO, INC.
Reel/Frame 039779/0710 →
Priority Claims (1)
JP 2014-019669 · Feb 4, 2014 · national
Continuity (2)
Continuation PCTJP2015052978 · Feb 3, 2015
Related Publication 20160343559A1 · Nov 24, 2016