Systems and methods for mapping and ablation in the bladder
The present disclosure relates to the field of tissue mapping and ablation. Specifically, the present disclosure relates to expandable medical devices for identifying and treating local anatomical abnormalities within a body lumen. More specifically, the present disclosure relates to systems and methods of focal treatment for overactive bladders.
1. A medical device, comprising:
a catheter comprising a proximal end, a distal end, and a lumen extending therebetween;
a plurality of disc-shaped balloons stacked along a longitudinal axis of the catheter proximate the distal end of the catheter, the plurality of disc-shaped balloons comprising a first balloon, a second balloon on either side of the first balloon, and a third balloon on either side of the stack of first and second balloons, wherein the first balloon has a greater maximum volume than each of the second balloons on either side of the first balloon, and wherein each of the second balloons have a greater maximum volume than each of the third balloons on either side of the stack of first and second balloons;
a plurality of tubes traversing at least a portion of the catheter lumen, wherein a first end of each of the plurality of tubes is fluidly connected to a different one of the plurality of disc-shaped balloons;
a plurality of electrodes carried about a surface of each of the plurality of disc-shaped balloons; and an additional tube traversing at least a portion of the catheter lumen, the additional tube configured to introduce a fluid into the human bladder.
2. The medical device of claim 1 , wherein each of the plurality of disc-shaped balloons comprises a compliant polymer selected from the group consisting of silicone rubbers, polyurethanes, butyl rubbers, latexes, styrene-isobutylene-styrene block copolymers and EPDM, or a non-compliant polymer selected from PEBAX, PET, PEN, PBT, PEEK, Hytrel, polyurethane and nylon.
3. The medical device of claim 1 , wherein each of the plurality of balloons is configured to move between a collapsed configuration and an expanded configuration.
4. The medical device of claim 1 , wherein a second end of each of the plurality of tubes is in fluid communication with a fluid source, and wherein each of the plurality of disc-shaped balloons moves from a collapsed configuration to an expanded configuration by flowing a fluid from the fluid source into the lumen of each of the plurality of disc-shaped balloons.
5. The medical device of claim 1 , wherein each of the plurality of electrodes is adapted to contact a wall of the body lumen when the plurality of disc-shaped balloons are in an expanded configuration.
6. The medical device of claim 1 , wherein each of the plurality of disc-shaped balloons is slidable along the distal end of the catheter.
7. The medical device of claim 1 , wherein each of the plurality of disc-shaped balloons is biased from an adjacent balloon by a spring disposed about the catheter.
8. The medical device of claim 1 , wherein the plurality of disc-shaped balloons are positioned around a longitudinal axis of the catheter.
9. The medical device of claim 1 , further comprising a plurality of conducting wires, wherein a first end of each of the plurality of conducting wires is electrically coupled to a different one of the plurality of electrodes.
10. The medical device of claim 9 , wherein a second end of each of the plurality of conducting wires is electrically coupled to an ablation energy source.
11. The medical device of claim 9 , wherein a second end of each of the plurality of conducting wires is electrically coupled to an electrical activity processing system.
12. The medical device of claim 1 ,
wherein at least a portion of at least one of the plurality of balloons is fluid permeable.
13. The medical device of claim 1 , wherein the plurality of disc-shaped balloons have a total maximum volume of approximately 1000 ml.
14. The medical device of claim 1 , wherein the plurality of disc-shaped balloons are spaced along a longitudinal axis of the catheter.
15. The medical device of claim 1 , wherein each of the plurality of disc-shaped balloons is expandable independent of the other balloons.
16. The medical device of claim 1 , wherein the plurality of disc-shaped balloons are inflatable to each have substantially the same volume.
17. A medical device, comprising:
a catheter comprising a proximal end, a distal end, and a lumen extending therebetween;
a plurality of disc-shaped balloons stacked along a longitudinal axis of the catheter proximate the distal end of the catheter and including a central first tier balloon, a second tier balloon on either sides of the central first tier balloon, and a third tier balloon on either side of the stack of first and second tier balloons, wherein the first tier balloon has a greater maximum volume than each of the second tier balloons on either side of the first tier balloon, and wherein each of the second tier balloons have a greater maximum volume than each of the third tier balloons on either side of the stack of first and second tier balloons;
a plurality of tubes traversing at least a portion of the catheter lumen, wherein a first end of each of the plurality of tubes is fluidly connected to a different one of the plurality of balloons;
a plurality of electrodes carried about a surface of each of the plurality of balloons; and
an additional tube traversing at least a portion of the catheter lumen, the additional tube configured to introduce a fluid into the human bladder.
18. The medical device of claim 17 , wherein each of the plurality of disc-shaped balloons is expandable independent of the other balloons.
19. The medical device of claim 17 , wherein the first tier balloon has a different maximum volume than the second tier balloons and the third tier balloons, the second tier balloons have a different maximum volume than the first tier balloon and the third tier balloons, and the third tier balloons have a different maximum volume than the first tier balloon and the second tier balloons.
20. A method, comprising:
introducing the medical device of claim 1 into a body lumen;
moving at least one of the plurality of disc-shaped balloons from a collapsed configuration to an expanded configuration such that the plurality of electrodes carried about the surface of the plurality of the disc-shaped balloons contact a tissue of the body lumen;
measuring the electrical activity within the tissue of the body lumen in contact with each of the plurality of electrodes;
identifying ones from the plurality of electrodes that detected an elevated electrical activity within the tissue of the body lumen; and
applying electrical energy to the ones from the plurality of electrodes that identified elevated electrical activity.