IP Library › Granted Patent US 9,828,419
Granted Patent B2
US 9,828,419 · App. 15/230,188 · Granted Nov 28, 2017

Antibody and antibody-containing composition

Inventor: Yasuhiro Tsukamoto (Osaka, JP)
Assignees: Ostrich Pharma KK; Immortal Spirit Limited
C07K16/1271C07K16/084C07K16/085C07K16/1045C07K16/1063C07K16/1267C07K2317/11C07K2317/23C07K2317/76C12N2710/14043
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Quick Facts
Patent No.
US 9,828,419
App. No.
15/230,188
Granted
Nov 28, 2017
Kind
B2
Abstract

For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.

Claims (5)

1. A method of treating skin of a subject, comprising administering a composition comprising ostrich polyclonal antibodies against antigens from a lysis solution of a microbial cell to the subject, wherein the antigens comprise enterotoxin, super antigen TSST-1, coagulase, and protease, the microbial cell comprises Staphylococcus aureus or Propionibacterium acnes , and wherein the subject has atopy, acne, or both.

2. The method of claim 1 , wherein the microbial cell comprises Staphylococcus aureus.

3. The method of claim 1 , wherein the microbial cell comprises Propionibacterium acnes.

4. The method of claim 1 , wherein the microbial cell comprises Staphylococcus aureus and Propionibacterium acnes.

5. The method of claim 1 , wherein the composition comprises a base.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2024
From: IMMORTAL SPIRIT LIMITED
To: ZEAL COSMETICS INC.
Reel/Frame 067214/0842 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 25, 2016
From: TSUKAMOTO, YASUHIRO
To: OSTRICH PHARMA KK; IMMORTAL SPIRIT LIMITED
Reel/Frame 039544/0332 →
Priority Claims (1)
JP 2011-179378 · Aug 19, 2011 · national
Continuity (2)
Division 14239776
Related Publication 20160340416A1 · Nov 24, 2016