Biofluid collection and filtration device
A filtration device is disclosed for filtering debris from a biofluid sample. In at least one embodiment, the filtration device provides a collection container having a collection chamber defined by a flexible wall, a mouth fluidly communicating with the collection chamber and formed through the collection container at a top end, and a filter device defining a bottom to the collection chamber. A quantitative container has a quantitative chamber in fluid communication with the filter device with the filter device separating the collection chamber from the quantitative chamber. A biofluid sample is introduced into the collection chamber through the mouth, and when the mouth with a collection chamber cap, the flexible wall of the collection container is squeezed to reduce the volume of the collection chamber and force the biofluid sample through the filter device, the filtered biofluid sample thereafter being contained within the quantitative chamber.
1. A filtration device for filtering debris from a biofluid sample to generate a filtered biofluid sample, the filtration device comprising:
a collection container comprising a collection chamber defined by a flexible wall, wherein an entirety of the flexible wall is flexible, a mouth fluidly communicating with the collection chamber and formed through the collection container at a top end, and a filter device defining a bottom of the collection chamber;
a quantitative container comprising a quantitative chamber in fluid communication with the filter device with the filter device separating the collection chamber from the quantitative chamber, an orifice formed through the quantitative container; and
a collection chamber cap selectively sealing the mouth of the collection chamber;
wherein, a biofluid sample is capable of being introduced into the collection chamber through the mouth; and
wherein, when the collection chamber cap is sealed over the mouth, the flexible wall of the collection container is capable of being squeezed to reduce the volume of the collection chamber and force the biofluid sample through the filter device, the filtered biofluid sample thereafter being contained within the quantitative chamber.
2. The filtration device according to claim 1 , wherein the filter device has a pore size of about 0.2 μm to about 50.0 μm.
3. The filtration device according to claim 1 , wherein the quantitative chamber has a volume of about 0.5 mL to about 5.0 mL.
4. The filtration device according to claim 1 , wherein the quantitative chamber has a volume of 1 mL.
5. A system for processing a biofluid sample, the system comprising a filtration device as defined in claim 1 .
6. The filtration device according to claim 1 , wherein the quantitative container is a nozzle converging to the orifice.
7. The filtration device according to claim 6 , wherein the orifice has a diameter sized so that the filtered biofluid sample drips through the orifice in droplets, each droplet volume ranging between 1 microliter to 200 microliters.
8. The filtration device according to claim 1 , wherein a collection device is detachably fitted to the mouth of the collection container, wherein, in use, the collection device receives the biofluid sample and guides the biofluid sample into the mouth to be collected in the collection chamber.
9. The filtration device according to claim 8 , wherein the collection device is a funnel with a stem, the stem engaging the mouth when the funnel is attached to the collection container.
10. The filtration device according to claim 1 , wherein the collection chamber cap is connected to the collection container through a collection chamber cap living hinge, the collection chamber cap includes a bung for frictionally engaging the mouth.
11. The filtration device according to claim 1 , wherein the quantitative chamber further comprises a dispenser cap for selectively sealing the orifice.
12. The filtration device according to claim 11 , wherein the dispenser cap is connected to the quantitative container through a dispenser cap living hinge.
13. The filtration device according to claim 11 , wherein the dispenser cap seals the filtered biofluid sample within the quantitative chamber when the dispenser cap is connected to the quantitative container.
14. A filtration device for filtering debris from a biofluid sample to generate a filtered biofluid sample, the filtration device comprising:
a collection container comprising a collection chamber defined by a flexible wall, wherein an entirety of the flexible wall is flexible, a mouth fluidly communicating with the collection chamber and formed through the collection container at a top end, and a filter device defining a bottom of the collection chamber;
a quantitative container comprising a quantitative chamber in fluid communication with the filter device with the filter device separating the collection chamber from the quantitative chamber, an orifice formed through the quantitative container, the quantitative container being shaped as a nozzle converging to the orifice;
a collection chamber cap selectively sealing the mouth of the collection chamber; and
a collection device detachably fitted to the mouth of the collection container;
wherein, a biofluid sample is capable of being introduced into the collection chamber through the mouth;
wherein, in use, the collection device receives the biofluid sample and guides the biofluid sample into the mouth to be collected in the collection chamber; and
wherein, when the collection chamber cap is sealed over the mouth, the flexible wall of the collection container is capable of being squeezed to reduce the volume of the collection chamber and force the biofluid sample through the filter device, the filtered biofluid sample thereafter being contained within the quantitative chamber.
15. The filtration device according to claim 14 , wherein the orifice has a diameter sized so that the filtered biofluid sample drips through the orifice in droplets, each droplet volume ranging between 1 microliter to 200 microliters.
16. The filtration device according to claim 14 , wherein the collection device is a funnel with a stem, the stem engaging the mouth when the funnel is attached to the collection container.
17. The filtration device according to claim 14 , wherein the collection chamber cap is connected to the collection container through a collection chamber cap living hinge, the collection chamber cap includes a bung for frictionally engaging the mouth.