IP Library Granted Patent US 9,943,686
Granted Patent B2
US 9,943,686 · App. 15/231,468 · Granted Apr 17, 2018

Method and device for treating sleep apnea based on tongue movement

Inventor: Adi Mashiach (Tel Aviv, IL)
Assignee: NYXOAH SA
A61N1/3601A61B5/0031A61B5/11A61B5/113A61B5/4818A61B5/682A61F5/566A61N1/0514A61N1/0526A61N1/0551A61N1/0553A61N1/36003A61N1/3606A61N1/3611A61N1/36057A61N1/36075A61N1/36117A61N1/36135A61N1/36146A61N1/3756A61N1/3787A61N1/37223A61N1/37229A61N2/006A61B5/4519A61B5/6822A61B5/6833A61B5/6876A61B2560/0219A61B2562/164A61N2/02
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Quick Facts
Patent No.
US 9,943,686
App. No.
15/231,468
Granted
Apr 17, 2018
Kind
B2
Abstract

A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

Claims (25)

1. A method for treating sleep disordered breathing via an implant unit implanted in a location proximate a tongue of the subject, the method comprising:

receiving a signal associated with the implant unit, the signal being indicative of a tongue movement of the subject;

determining, based on the signal, that the tongue movement is representative of sleep disordered breathing; and

communicating a modulation control signal to the implant unit to activate neuromuscular tissue within the tongue via at least one pair of electrodes associated with the implant unit, wherein the modulation control signal causes modulation of a hypoglossal nerve of the subject in response to an electric field generated by the at least one pair of electrodes,

wherein the modulation is confined to a medial branch of the hypoglossal nerve and initiated from a single modulation site along the medial branch to cause modulation of terminal fibers of the medial branch of the hypoglossal nerve.

2. The method of claim 1 , wherein the at least one pair of electrodes are configured so as to cause contractions of a genioglossus muscle of the subject via modulation of the medial branch of the subject's hypoglossal nerve.

3. The method of claim 2 , wherein the at least one pair of electrodes are configured for location adjacent to a horizontal compartment of the genioglossus muscle.

4. The method of claim 1 , further comprising receiving the signal associated with the implant unit via an antenna configured for location external to the body of the subject.

5. The method of claim 4 , wherein the signal associated with the implant unit is indicative of a degree of coupling between the antenna configured for location external to the body of the subject and an antenna associated with the implant unit.

6. The method of claim 5 , further comprising determining the tongue movement based on the degree of coupling, wherein the degree of coupling is based on a relative motion between the antenna configured for location external to the body of the subject and the antenna associated with the implant unit.

7. The method of 5 , further comprising determining a characteristic of the modulation control signal based on the degree of coupling between the antenna configured for location external to the body of the subject and the antenna associated with the implant unit.

8. The method of claim 5 , wherein the degree of coupling between the antenna configured for location external to the body of the subject and the antenna associated with the implant unit includes one of a measure selected from capacitive coupling, radiofrequency coupling, and inductive coupling.

9. A device for treating sleep disordered breathing via an implant unit implanted in a location proximate a tongue of the subject, the device comprising:

a housing configured for location external to a body of the subject, the housing including a processor further configured to:

receive a signal associated with the implant unit, the signal being indicative of a tongue movement of the subject;

determine, based on the signal, that the tongue movement is representative of sleep disordered breathing; and

communicate a modulation control signal to the implant unit to activate neuromuscular tissue within the tongue via at least one pair of electrodes associated with the implant unit, wherein the modulation control signal causes modulation of a hypoglossal nerve of the subject in response to an electric field generated by the at least one pair of electrodes,

wherein the modulation is confined to a portion of the hypoglossal nerve distal of a terminal bifurcation of the hypoglossal nerve into lateral and medial branches.

10. The device of claim 9 , wherein the at least one pair of electrodes are configured so as to cause contractions of a genioglossus muscle of the subject via modulation of the subject's hypoglossal nerve.

11. The device of claim 9 , wherein the at least one pair of electrodes are configured for location adjacent to a horizontal compartment of the genioglossus muscle.

12. The device of claim 9 , wherein the housing is electrically coupled to an antenna and the processor is further configured to receive the signal associated with the implant unit via the antenna.

13. The device of claim 12 , wherein the signal associated with the implant unit is indicative of a degree of coupling between the antenna coupled to the housing and an antenna associated with the implant unit.

14. The device of claim 13 , wherein the processor is further configured to determine the tongue movement based on the degree of coupling, wherein the degree of coupling is based on a relative motion between the antenna coupled to the housing and the antenna associated with the implant unit.

15. The device of 13 , wherein the processor is further configured to determine a characteristic of the modulation control signal based on the degree of coupling between the antenna coupled to the housing and the antenna associated with the implant unit.

16. The device of claim 13 , wherein the degree of coupling between the antenna of the housing and the antenna associated with the implant unit includes one of a measure selected from capacitive coupling, radiofrequency coupling, and inductive coupling.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2018
From: MASHIACH, ADI
To: NYXOAH SA
Reel/Frame 047125/0719 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 12, 2016
From: MASHIACH, ADI, DR.; SCHOLZ, OLIVER
To: NYXOAH SA
Reel/Frame 040323/0366 →
Continuity (23)
Continuation 14041598 · Sep 30, 2013
Continuation In Part 13629690 · Sep 28, 2012
Continuation In Part 13629694 · Sep 28, 2012
Continuation In Part 13629701 · Sep 28, 2012
Continuation In Part 13629712 · Sep 28, 2012
Continuation In Part 13629725 · Sep 28, 2012
Continuation In Part 13629730 · Sep 28, 2012
Continuation In Part 13629741 · Sep 28, 2012
Continuation In Part 13629748 · Sep 28, 2012
Continuation In Part 13629757 · Sep 28, 2012
Continuation In Part 13629762 · Sep 28, 2012
Continuation In Part 13629793 · Sep 28, 2012
Continuation In Part 13629819 · Sep 28, 2012
Continuation In Part 13630392 · Sep 28, 2012
Continuation In Part 13629721 · Sep 28, 2012
Continuation In Part 13629686 · Sep 28, 2012
Continuation In Part 12642866 · Dec 21, 2009
Continuation In Part 12581907 · Oct 20, 2009
Continuation In Part 12642866 · Dec 21, 2009
Continuation In Part 12581907 · Oct 20, 2009
Provisional Application 61541651 · Sep 30, 2011
Provisional Application 61657424 · Jun 8, 2012
Related Publication 20160346537A1 · Dec 1, 2016