Pharmaceutical products from fungal strains
Disclosed herein are compositions comprising an isolated cellulose degrading fungus and pharmaceutical substances produced by the fungus.
1. An animal feed formulation to provide increased resistance to infection comprising:
animal feed, and
and an antibiotic amount of a fungal biomass comprising the biomass of a cellulose degrading fungus and a conditioned medium comprising an inhibitory substance, wherein said medium is conditioned by the cellulose degrading fungus cultured in a bioreactor on a feedstock that does not contain added glycerol,
wherein said cellulose degrading fungus comprises a characteristic selected from the group consisting of: a 5.8S ribosomal RNA gene sequence having at least 98% nucleotide sequencing identity with the nucleic acid of SEQ ID NO: 1; an ITS1 sequence with at least 98% sequence identity to SEQ ID NO: 2; an ITS2 sequence with at least 98% sequence identity to SEQ ID NO: 3; and a 28S ribosomal RNA gene sequence with at least 98% sequence identity to SEQ ID NO: 4, and
wherein the animal feed formulation comprises 1% to 90% fungal biomass by weight, and the animal feed provides nutrition in addition to the fungal biomass.
2. The animal feed formulation of claim 1 , wherein said cellulose degrading fungus comprises a species being the same as NRRL deposit Accession No: 50410.
3. The animal feed formulation of claim 1 , wherein the animal feed formulation is suitable for consumption by an animal selected from the group consisting of: cows, birds, pigs, cats, dogs, humans, rodents, fish, shrimp, prawns, and aquatic mammals.
4. The animal feed formulation of claim 1 , wherein the animal feed formulation is suitable for consumption by chickens or shrimp.
5. The animal feed formulation of claim 1 , wherein the fungal biomass is a dried fungal biomass.
6. The animal feed formulation of claim 1 , wherein said inhibitory substance is an antimicrobial substance.
7. The animal feed formulation of claim 1 , wherein said inhibitory substance is a bacteriostatic agent.
8. The animal feed formulation of claim 1 , wherein said inhibitory substance is a bacteriocidal agent.
9. The animal feed formulation of claim 1 , wherein said inhibitory substance is a bacteriocidal agent against Gram-negative bacterium.
10. The animal feed formulation of claim 9 , wherein said inhibitory substance is a bacteriocidal agent against Gram-positive bacterium.