IP Library Granted Patent US 10,653,725
Granted Patent B2
US 10,653,725 · App. 15/239,259 · Granted May 19, 2020

Methods for improving health of farmed fish

Inventors: Sigve Nordrum (Slependen, NO); Harald Takle (Ås, NO); Sven Martin Jørgensen (Ås, NO); Trygve Sigholt (Myre, NO)
Assignees: Aker BioMarine Antarctic AS; Biomar Group
A61K35/612A23K10/22A23K20/158A23K40/10A23K50/80A61K9/0056A61K9/16A61K31/202
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Quick Facts
Patent No.
US 10,653,725
App. No.
15/239,259
Granted
May 19, 2020
Kind
B2
Abstract

The present invention provides methods for treating and preventing viral disease in farmed fish. In particular, the present invention relates to compositions and methods for improving heart health in farmed salmon.

Claims (18)

1. A method of improving a parameter of heart health fish comprising:

feeding fish a dietary ration comprising an amount of krill meal effective to improve one or more parameters of heart health in said fish, wherein the ration has a fatty acid content and from 2% to 10% of the fatty acids in the ration are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) combined and the ratio of EPA to DHA is from 0.7 to 1.8.

2. The method of claim 1 , wherein said one or more parameters of heart health are selected from the group consisting of one or more of improved cardiac fatty acid composition, improved erythrocyte fatty acid composition, increased rate of growth, increased body mass, increased body length, increased ventricle mass relative to body mass, increased ventricle mass relative to body length, improved swimming capacity, decreased maximum heart rate, and increased thickness of the compact myocardium.

3. The method of claim 2 , wherein said improved cardiac fatty acid composition and erythrocyte fatty acid composition comprises an increase in levels of linoleic acid (LA, 18:2n-6) and/or alpha-linolenic acid (ALA).

4. The method of claim 1 , wherein said ration is a pelleted ration.

5. The method of claim 1 , wherein said ration comprises from about 4% to 15% krill meal.

6. The method of claim 1 , wherein said ration comprises approximately 185-220 mg/g fatty acids and approximately 23-26% lipids.

7. The method of claim 6 , wherein from 3-7% of the fatty acids in said ration are EPA and DHA combined.

8. The method of claim 6 , wherein the ratio of EPA to DHA in said ration in between approximately 0.9 and 1.4.

9. The method of claim 1 , wherein said fish are infected with a viral disease.

10. A method of improving a parameter of heart health in fish comprising:

feeding fish a pelleted dietary ration comprising an amount of krill meal effective to improve one or more parameters of heart health quality in said fish, wherein said one or more parameters of heart health are selected from the group consisting of one or more of improved cardiac fatty acid composition, improved erythrocyte fatty acid composition, increased rate of growth, increased body mass, increased body length, increased ventricle mass relative to body mass, increased ventricle mass relative to body length, improved swimming capacity, decreased maximum heart rate, and increased thickness of the compact myocardium, wherein the ration has a fatty acid content and from 2% to 10% of the fatty acids in the ration are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) combined and the ratio of EPA to DHA is from 0.7 to 1.8.

11. The method of claim 10 , wherein said improved cardiac fatty acid composition and erythrocyte fatty acid composition comprises an increase in levels of linoleic acid (LA, 18:2n-6) and/or alpha-linolenic acid (ALA).

12. The method of claim 10 , wherein said ration is a pelleted ration.

13. The method of claim 10 , wherein said ration comprises from about 4% to 15% krill meal.

14. The method of claim 10 , wherein said ration comprises approximately 185-220 mg/g fatty acids and approximately 23-26% lipids.

15. The method of claim 14 , wherein from 3-7% of the fatty acids in said ration are EPA and DHA combined.

16. The method of claim 10 , wherein said fish are infected with a viral disease.

Assignments (2)
CHANGE OF NAME Recorded Mar 6, 2025
From: AKER BIOMARINE ANTARCTIC AS
To: THE QRILL COMPANY AS
Reel/Frame 070426/0958 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2022
From: NORDRUM, SIGVE; JØRGENSEN, SVEN MARTIN; TAKLE, HARALD; SIGHOLT, TRYGVE
To: AKER BIOMARINE ANTARCTIC AS
Reel/Frame 059770/0568 →
Continuity (2)
Provisional Application 62206006 · Aug 17, 2015
Related Publication 20170049824A1 · Feb 23, 2017