IP Library Granted Patent US 10,603,216
Granted Patent B2
US 10,603,216 · App. 15/241,612 · Granted Mar 31, 2020

Photodisruptive laser treatement of crystalline lens

Inventors: Ronald M. Kurtz (Irvine, CA); Ferenc Raksi (Mission Viejo, CA); Peter Goldstein (Santa Ana, CA)
Assignee: Alcon Inc.
A61F9/00838A61F9/008A61F9/009A61F2009/0087A61F2009/00851A61F2009/00895A61F2009/00897
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Quick Facts
Patent No.
US 10,603,216
App. No.
15/241,612
Granted
Mar 31, 2020
Kind
B2
Abstract

Apparatus and methods of treating a hard lens region of an eye with a laser where one method includes identifying a boundary of the hard lens region, selecting a laser-parameter to enable a photo disruptive procedure in the hard lens region and to control a spreading of bubbles in the hard lens region, modifying a mechanical property of a posterior portion of the hard lens region in a proximity of the identified boundary by the photo disruptive procedure, and modifying a mechanical property of a portion anterior to the modified posterior portion of the hard lens region by the photo disruptive procedure. The laser bubbles can be applied to form incisions which are non-transverse to an axis of the eye and intersect the lens fibers.

Claims (50)

1. A laser system for fragmenting a crystalline lens of an eye, comprising:

a pulsed laser that generates a laser beam of laser pulses; and

an optical delivery system comprising:

optics with a curved focal plane that receive the laser beam and focus the laser beam onto the crystalline lens, the optics comprising one or more lenses;

an XY scanner that scans the laser beam in x and y directions perpendicular to the propagation direction of the laser beam with a first scanning speed; and

a Z-scanner that scans the laser beam in a z direction parallel to the propagation direction of the laser beam with a second scanning speed slower than the first scanning speed, wherein the optical delivery system applies the laser beam to create incisions forming a plurality of layers in the crystalline lens of the eye on a layer-by-layer basis by:

scanning the laser beam with the XY scanner along the curved focal plane of the optics to create an incision of a layer that follows the curvature of the curved focal plane; and

scanning the laser beam with the Z scanner at the second scanning speed slower than the first scanning speed of the XY scanner to create the incision of the layer, without adjusting the Z scanner at the first scanning speed of the XY scanner.

2. The laser system of claim 1 , wherein the optical delivery system is configured to move a focal point of the laser in a posterior-to-anterior direction of the lens.

3. The laser system of claim 1 , wherein the optical delivery system is configured to control the laser to generate a laser beam with laser-parameters:

sufficient to create photodisruption in a selected lens region; and

insufficient to cause damage to a retina of the eye.

4. The laser system of claim 3 , wherein the optical delivery system is configured to control the pulsed laser to generate laser pulses with laser-parameters comprising:

an energy in the range of 0.5 microJ to 50 microJ;

a separation of adjacent target areas in the range of 1 micron to 100 microns;

a duration in the range of 0.005 picoseconds to 25 picoseconds; and

a repetition rate in the range of 1 kHz to 10 MHz.

5. The laser system of claim 1 , wherein:

the incisions are formed on a layer-by-layer basis without interrupting the application of the laser.

6. The system of claim 1 , wherein an orientation of a portion of the incision is one of an orientation intersecting fibers of the lens and an orientation non-transverse to an axis of the eye.

7. The system of claim 6 , wherein the incision has a spatial extent in a Z direction in the range of 0.5-10 mm, and in an X-Y plane in the range of 2-10 mm.

8. The system of claim 6 , wherein the non-transverse orientation of the incision is one of:

an orientation substantially parallel to the axis of the eye; and

an orientation making a less than 90 degree angle with the axis of the eye.

9. The laser system of claim 1 , wherein forming the incisions on a layer-by-layer basis comprises:

applying laser pulses to target locations within a posterior layer of the lens, the target locations belonging to two incisions or two segments of the same incision; and

applying laser pulses to target locations within a layer anterior to the posterior layer, the target locations belonging to the same two incisions or to the same two segments of the same incision.

10. The system of claim 1 , wherein the non-transverse orientation of the incision is one of:

an orientation substantially parallel to the axis of the eye; and

an orientation making a less than 90 degree angle with the axis of the eye.

11. The system of claim 1 , wherein an orientation of the incision is aligned with a preferential direction of expansion of the bubbles.

12. The system of claim 1 , wherein the laser pulses are scanned in a continuous manner to form the incision without repositioning the laser or interrupting the application of the laser.

13. The system of claim 1 , wherein the incision has a form aligned with the axis of the eye, the form being of at least one of:

a cylinder, a set of concentric cylinders, a set of cylinders connected by one or more connecting line, a curved surface, a cone, a spiral, a layered spiral with smooth lines connecting layers of the spiral and a tilted cylinder.

14. The system of claim 1 , wherein the incision has a form aligned with the axis of the eye, the form being at least one of:

a plane, two or more crossing planes, a combination of planes and connecting arcs, and a combination of planes and cylinders.

15. The system of claim 1 , wherein the optical delivery system is configured to scan the laser beam by:

applying the laser pulses to form a first ring with a first radius in a posterior layer of the lens;

applying the laser pulses to form a connector line between the first and a second ring in the posterior layer;

applying the laser pulses to form the second ring with a second radius in the posterior layer; and

repeating multiple times the formation of the first ring, the second ring and the connector line in layers sequentially anterior to the posterior layer,

wherein the first rings in the sequential layers form a first cylinder, the second rings form a second cylinder, the cylinders being connected by the connector lines.

16. The system of claim 15 , wherein the connector lines in sequential layers are one of:

aligned to form connector planes; and

not-aligned from layer to layer.

17. The system claim 1 , wherein the optical delivery system is configured to scan the laser beam to:

form a posterior spiral in a posterior layer;

form a smooth connector line starting near an end of the posterior spiral in the posterior layer, the connector line smoothly bending and rising to a central region of a layer anterior to the posterior layer; and

form an anterior spiral starting at the end of the smooth connector line in the central region of the anterior layer.

18. The system of claim 17 , wherein the posterior spiral and the anterior spiral are essentially aligned to form a spiral with an extent in the Z direction.

Assignments (3)
CONFIRMATORY DEED OF ASSIGNMENT EFFECTIVE APRIL 8, 2019 Recorded Dec 11, 2019
From: ALCON LENSX, INC.
To: ALCON INC.
Reel/Frame 051257/0218 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2017
From: KURTZ, RONALD M.; RAKSI, FERENC; GOLDSTEIN, PETER
To: LENSX LASERS, INC.
Reel/Frame 041133/0166 →
CHANGE OF NAME Recorded Jan 31, 2017
From: LENSX LASERS, INC.
To: ALCON LENSX, INC.
Reel/Frame 041567/0872 →
Continuity (4)
Continuation 12343418 · Dec 23, 2008
Continuation In Part 12205842 · Sep 5, 2008
Provisional Application 60970454 · Sep 6, 2007
Related Publication 20170087022A1 · Mar 30, 2017
Cited By (6)
US 12,226,345 US 12,245,813 US 12,245,974 US 12,465,523 US 12,629,246 US 12,642,699