IP Library › Granted Patent US 10,144,755
Granted Patent B2
US 10,144,755 · App. 15/256,345 · Granted Dec 4, 2018

Substituted nucleosides, nucleotides and analogs thereof

Inventors: Leonid Beigelman (San Mateo, CA); Guangyi Wang (Carlsbad, CA); David Bernard Smith (San Mateo, CA)
Assignee: Alios BioPharma, Inc.
C07H19/10C07H19/06C07H19/16C07H19/173C07H19/20C07H19/207C07H19/213
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Quick Facts
Patent No.
US 10,144,755
App. No.
15/256,345
Granted
Dec 4, 2018
Kind
B2
Abstract

Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HCV infection with one or more nucleotide analogs.

Claims (6)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt of the foregoing.

2. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt of the foregoing.

3. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt of the foregoing.

Assignments (2)
CHANGE OF NAME Recorded Oct 1, 2020
From: ALIOS BIOPHARMA, INC.
To: JANSSEN BIOPHARMA, INC.
Reel/Frame 053968/0536 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 6, 2016
From: BEIGELMAN, LEONID; WANG, GUANGYI; SMITH, DAVID BERNARD
To: ALIOS BIOPHARMA, INC.
Reel/Frame 039642/0115 →
Continuity (5)
Continuation 14836822 · Aug 26, 2015
Continuation 14135488 · Dec 19, 2013
Provisional Application 61890125 · Oct 11, 2013
Provisional Application 61745466 · Dec 21, 2012
Related Publication 20170037075A1 · Feb 9, 2017