Method of treating pain using an acetaminophen dimer ether-linked through phenolic hydroxyl groups
Provided herein is a method for treating pain in a subject without risking hepatotoxicity by administering a pharmaceutical composition containing an acetaminophen dimer compound wherein the phenolic hydroxyl groups of two acetaminophen molecules are linked via an ethylene spacer.
1. A method of treating acute or chronic pain in a subject which subject's symptoms stem from a condition other than fascioliasis, the method comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a pharmaceutically acceptable carrier or excipient and an acetaminophen dimer compound having the Formula (I):
or a pharmaceutically acceptable salt or solvate thereof.
2. The method of claim 1 wherein the subject is experiencing acute pain.
3. The method of claim 1 wherein the subject is experiencing chronic pain.
4. The method of claim 1 wherein the subject suffers from gastrointestinal acidity or gastrointestinal reflux disease.
5. The method of claim 1 wherein the subject suffers from cancer.
6. The method of claim 1 wherein the pharmaceutical composition further comprises a barbiturate, opioid, antihistamine, caffeine, diphenhydramine, dextromethorphan, pseudoepinephrine or combinations thereof.