Multiblock copolymer films, methods of making same, and uses thereof
A method for forming an isoporous graded film comprising multiblock copolymers and isoporous graded films. The films have a surface layer and a bulk layer. The surface layer can have at least 1×10 14 pores/m 2 and a pore size distribution (d max /d min )) of less than 3. The bulk layer has an asymmetric structure. The films can be used in filtration applications.
1. An polymeric isoporous graded film comprising a poly(isoprene-b -styrene-b-4-vinylpyridine) triblock copolymer,
wherein the triblock copolymer has a poly(isoprene) volume fraction ranging from 0.13 to 0.43, a poly(styrene) volume fraction ranging from 0.4 to 0.64, and a poly((4-vinyl)pyridine) volume fraction ranging from 0.04 to 0.32,
wherein the film has a surface layer having a thickness of from 20 nm to 500 nm and a plurality of pores 5 nm to 100 nm in size and a pore density of at least 1×10 14 pores/m 2 , and
wherein the film has a bulk layer having a thickness of from 5 microns to 500 microns, pores having a size of from 10 nm to 100 microns, and an asymmetric substructure.
2. An polymeric isoporous graded film comprising,
a triblock polymer having:
a first terminal block incorporating a hydrophobic polymer selected from the group consisting of poly(isoprene), poly(butadiene), poly(butylene), and poly(isobutylene); and
a second terminal block comprising a hydrogen-bonding polymer selected from the group consisting of poly((4-vinyl)pyridine), poly((2-vinyl) pyridine), poly(ethylene oxide), a poly(methacrylate), poly(acrylic acid), and poly(hydroxystyrene), and
a hydrophobic block located between the first terminal block and the second terminal block, the hydrophobic block selected from the group consisting of a poly(styrene), polyethylene, polypropylene, polyvinyl chloride, and polytetrafluoroethylene,
wherein the film has a surface layer having a thickness of from 20 nm to 500 nm and a plurality of pores 5 nm to 100 nm in size and a pore density of at least 1×10 14 pores/m 2 ,
wherein the film has a bulk layer having a thickness of from 5 microns to 500 microns, pores having a size of from 10 nm to 100 microns, and an asymmetric substructure, and
wherein the triblock copolymer has a poly(isoprene) volume fraction ranging from 0.13 to 0.43, a poly(stvrene) volume fraction ranging from 0.4 to 0.64, and a poly((4-vinyl)pyridine) volume fraction ranging from 0.04 to 0.32.
3. The film of claim 1 , wherein the film further comprises a homopolymer or small molecule.
4. The film of claim 3 , wherein the molar ratio of multiblock copolymer to homopolymer is from 1:0.05 to 1:10 or the molar ratio of multiblock copolymer to small molecule is from 1:1 to 1:1000.
5. The film of claim 1 , wherein the film further comprises at least one inorganic material, wherein the at least one inorganic material is disposed on at least a portion of the film.
6. The film of claim 5 , wherein the at least one inorganic material is a plurality of metal nanoparticles, wherein the metal nanoparticles comprise one or more metals.
7. A device comprising a polymeric isoporous graded film according to claim 1 .
8. The device of claim 7 , wherein the device is a filtration device.
9. The device of claim 8 wherein the filtration device is an ultrafiltration device.
10. The device of claim 8 wherein the filtration device is a virus filtration device.
11. The device of claim 8 wherein the filtration device is a protein filtration device.
12. The device of claim 7 wherein the device is a virus or protein purification device.
13. The isoporous graded film of claim 1 , wherein the triblock copolymer has a molecular weight ranging from 37.5 to 166.8 kg/mol.
14. The isoporous graded film of claim 1 , wherein the triblock copolymer has a polydispersity index (PDI) ranging from 1.02 to 1.32.
15. The isoporous graded film of claim 1 , wherein the pores of the surface layer exhibit a square packed lattice.