Anti-vascular disease and antitumor pharmaceutical composition and use thereof
An anti-vascular diseases and antitumor pharmaceutical composition is provided in the present invention, and it includes effective ingredients including bleomycin antitumor antibiotic, adrenal glucocorticoid, epinephrine or pharmaceutically acceptable salts thereof in a weight ratio of (1-8):(2-5):(0.00005-0.001). The pharmaceutical composition provided can be used for treatment of vascular diseases and tumors.
1. An anti-vascular malformation pharmaceutical composition, wherein the pharmaceutical composition comprises effective ingredients comprising pingyangmycin, dexamethasone and epinephrine or pharmaceutically acceptable salts thereof in a weight ratio of 7:4.3755:0.00035.
2. The pharmaceutical composition according to claim 1 , wherein a total weight of the pingyangmycin, dexamethasone, and epinephrine accounts for 20%-90% of the weight of the pharmaceutical composition.
3. The pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition further comprises a pharmaceutically acceptable auxiliary.
4. The pharmaceutical composition according to claim 3 , wherein the pharmaceutically acceptable auxiliary comprises at least one of a pH regulator and mannitol.
5. The pharmaceutical composition according to claim 1 , wherein the pharmaceutical composition is in a dosage form of injection, freeze-dried powder, or microspheres.
6. The pharmaceutical composition according to claim 5 , wherein the microspheres are albumin microspheres, magnetic nano-microspheres, control-released magnetic nano-microspheres, or cellular targeted magnetic nano-microspheres.
7. A method for treating vascular malformations, comprising the step of:
preparing a medication comprising the pharmaceutical composition of claim 1 ;
administering the medication to a patient suffering from the vascular malformations.
8. The method for treating vascular malformations, comprising the step of:
preparing a medicine comprising the pharmaceutical composition of claim 2 ;
administering the medication to a patient suffering from the vascular malformations.
9. The method for treating vascular malformations, comprising the step of:
preparing a medicine comprising the pharmaceutical composition of claim 3 ;
administering the medication to a patient suffering from the vascular malformations.
10. The method for treating vascular malformations, comprising the step of:
preparing a medicine comprising the pharmaceutical composition of claim 4 ;
administering the medication to a patient suffering from the vascular malformations.
11. The method for treating vascular malformations, comprising the step of:
preparing a medicine comprising the pharmaceutical composition of claim 5 ;
administering the medication to a patient suffering from the vascular malformations.
12. The method for treating vascular malformations, comprising the step of:
preparing a medicine comprising the pharmaceutical composition of claim 6 ;
administering the medication to a patient suffering from the vascular malformations.