Automatic analysis apparatus
View Patent ↗An automatic analysis apparatus is capable of replacing circulated water in a reaction vessel and continuously cooling a light source lamp without stopping an operation for measuring a specimen. In an operation state, a drain electromagnetic valve 49 is opened to drain reaction vessel water outside and when the water level reaches a measurement limit water level, the drain electromagnetic valve 49 is closed. The reaction vessel water is supplied by starting a water supply pump, opening a water supply electromagnetic valve and when the water level has reached a full water level, the water supply electromagnetic valve is closed, and the water supply pump is stopped. In a state other than the operation state, the reaction vessel water is drained outside. When the water level has reached a circulation limit water level, the drain electromagnetic valve is closed.
1. An automatic analysis apparatus comprising:
a reaction container moving mechanism including a reaction vessel configured to hold water and a plurality of reaction containers for containing a specimen and a reagent arranged in the reaction container moving mechanism and which are immersed in the water in the reaction vessel, and the reaction container moving mechanism is configured to move the reaction containers thereon;
a light source lamp configured to irradiate a reaction container among the plurality of reaction containers arranged in the reaction vessel of the reaction container moving mechanism with light;
a photometer configured to measure the light emitted from the light source lamp and passed through the reaction container;
a discharge mechanism configured to discharge the water in the reaction vessel;
a water supply mechanism configured to supply water into the reaction vessel;
a reaction vessel water level detector including a first water level detector configured to detect that a water level of the water in the reaction vessel is a full water level and a second water level detector configured to detect that the water level of the water in the reaction vessel is a measurement limit water level which is lower than the full water level and higher than a position of an optical axis of the light emitted from the light source lamp; and
a control unit connected to the reaction container moving mechanism, the light source lamp, the photometer, the discharge mechanism, and the water supply mechanism, the control unit programmed to control operations of the reaction container moving mechanism, the light source lamp, and the photometer to analyze the specimen in the reaction container, and programmed to control operations of the discharge mechanism and the water supply mechanism based on the water level of the reaction vessel water detected by the reaction vessel water level detector.
2. The automatic analysis apparatus according to claim 1 , wherein
the control unit is programmed to perform a reaction vessel water replacing operation in which the water in the reaction vessel is drained to the measurement limit water level by controlling the discharging mechanism when the water level of the water in the reaction vessel is the full water level, and the water is supplied to the full water level by controlling the water supply mechanism when the water level of the water in the reaction vessel reaches the measurement limit water level.
3. The automatic analysis apparatus according to claim 2 , wherein
the reaction vessel water level detector further includes a third water level detector configured to detect that the water level of the water in the reaction vessel is a circulation limit water level which is lower than the measurement limit water level and higher than a bottom surface of the reaction vessel,
the control unit is programmed to:
in a measuring period when the photometer measures the light passed though the reaction container, perform a water supply and discharge operation control in which the water in the reaction vessel is drained until the water level of the water in the reaction vessel reaches the measurement limit water level by controlling the discharging mechanism when the water level of the water in the reaction vessel is the full water level, and the water is supplied into the reaction vessel until the water level in the reaction vessel reaches the full water level by controlling the water supply mechanism when the water level of the water in the reaction vessel reaches the measurement limit water level, and
in a period other than the measuring period perform a water supply and discharge operation control in which the water is drained until the water level of the water in the reaction vessel reaches the circulation limit water level by controlling the discharging mechanism when the water level of the water in the reaction vessel is the full water level, and the water is supplied until the water level of the water in the reaction vessel reaches the full water level by controlling the water supply mechanism when the water level of the water in the reaction vessel reaches the circulation limit water level.
4. The automatic analysis apparatus according to claim 3 , wherein
the control unit is programmed to repeat the water supply and discharge operation control during the measuring period at a predetermined frequency.
5. The automatic analysis apparatus according to claim 3 , wherein
the control unit is programmed to repeat the water supply and discharge operation control in the period other than the measuring period at a predetermined frequency.
6. The automatic analysis apparatus according to claim 3 , wherein
the circulation limit water level is set to be a level at which the water supply mechanism is capable of supplying water to the reaction vessel from the circulation limit water level to the measurement limit water level in a period of time from the period when the photometer does not perform the measurement to a start of the measuring period by the photometer.
7. The automatic analysis apparatus according to claim 3 , wherein
the control unit is programmed to, in a case where the water supply and discharge operation control in a period other than the measuring period is performed and the water level in the reaction vessel is lower than the measurement limit water level, control the photometer to wait until the water level in the reaction vessel reaches the measurement limit water level restart the measurement of the light.
8. The automatic analysis apparatus according to claim 2 , further comprising:
a reagent dispenser configured to dispense a reagent to the reaction container,
wherein the control unit is programmed to, after performing the reaction vessel water replacing operation, control the reagent dispenser to suction a surfactant to defoam and improve an antibacterial activity and electrical conductivity and discharge the surfactant in the reaction vessel.
9. The automatic analysis apparatus according to claim 2 , further comprising:
a display unit,
wherein another reaction container, for containing liquid of which an absorbance is known, is immersed in the water in the reaction vessel, and
wherein the control unit is programmed to:
control the photometer to measure the absorbance of the liquid in the other reaction container immersed in the water in the reaction vessel of the reaction container moving mechanism,
determine whether the reaction vessel water is abnormal by comparing the measured absorbance with the known absorbance, and
cause the display unit to display a warning when the reaction vessel water is determined to be abnormal.