IP Library Granted Patent US 10,406,375
Granted Patent B2
US 10,406,375 · App. 15/321,520 · Granted Sep 10, 2019

Apparatus for applying nitric oxide to a treatment site

Inventors: Andre DiMino (Woodcliff Lake, NJ); Matthew Drummer (Fort Lee, NJ); Howard Nelson (Lawrenceville, NJ); Michael Preston (Orangeburg, NY)
Assignee: ORIGIN, INC.
A61N1/44A61K33/00A61M35/003C01B21/203A61M2205/18A61M2205/27A61M2205/3327A61M2205/505A61M2205/584A61M2230/50
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,406,375
App. No.
15/321,520
Granted
Sep 10, 2019
Kind
B2
Abstract

A device for generating and delivering Nitric Oxide (NO) to a treatment site includes a main unit, an applicator, a connector hose, and a mobile stand. The main unit provides power and a gas to the applicator via the connector hose. The applicator includes a plasma generator for generating NO in a plasma state. The main unit including a user interface to enable a user to control at least one operational aspect of the device. The applicator includes a pistol grip handle, a trigger for actuating the plasma generator, a hose connection for coupling to the connector hose, and a cowl portion for spacing a tip of the plasma generator at a predetermined distance from a treatment site. Sensors are provided with the applicator for sending feedback and monitoring application site temperature, proximity to the application, applicator motion and the like.

Claims (21)

1. A device for generating and delivering NO to a treatment site, comprising:

a main unit;

an applicator;

a connector hose;

and a mobile stand;

wherein the main unit provides power and a gas to the applicator via the connector hose, the applicator including a plasma generator for generating Nitric Oxide (NO), the applicator including a proximity sensor to enable a user to monitor a relative distance between the applicator and the treatment site, and a color illuminator disposed adjacent to a front end of the applicator for providing a color that is changeable to indicate a warning or an error, and wherein the color illuminator is configured for projecting the color on the treatment site that is changeable to indicate the warning or the error.

2. The device of claim 1 , the main unit including a user interface to enable the user to control at least one operational aspect of the device.

3. The device of claim 2 , the user interface comprising a touch screen.

4. The device of claim 1 , the applicator comprising:

a pistol grip handle;

a trigger for actuating the plasma generator;

a hose connection for coupling to the connector hose; and

a cowl portion for spacing a tip of the plasma generator at a predetermined distance from the treatment site.

5. The device of claim 4 , the cowl portion including a plurality of ventilation holes along a length of the cowl portion to facilitate cooling of the device.

6. The device of claim 1 , further comprising a passive infrared skin temperature sensor to monitor a temperature of the treatment site such that the temperature is maintainable within a predetermined range.

7. The device of claim 1 , wherein the proximity sensor is configured to deactivate the device if the applicator is placed closer than a predetermined distance from the treatment site.

8. The device of claim 1 , further comprising a motion sensor disposed in or on the applicator, the motion sensor comprising a multi-axis accelerometer for measuring motion of the applicator.

9. The device of claim 8 , wherein the motion sensor is configured to deactivate the device if the applicator is not moved sufficiently to prevent over-treating of the treatment site.

10. The device of claim 1 , wherein the device is configured to produce a stream of air with a composition of a plasma species that contains a medically significant amount of NO.

11. The device of claim 10 , wherein the medically significant amount of NO is 2,500 parts per million (ppm) NO or less.

12. The device of claim 10 , wherein the medically significant amount of NO is 3,500 parts per million (ppm) NO or less.

Assignments (5)
SECURITY INTEREST Recorded Sep 6, 2024
From: ORIGIN LIFE SCIENCES, INC.
To: DISTRICT 2 CAPITAL FUND LP
Reel/Frame 068515/0219 →
CHANGE OF NAME Recorded Sep 12, 2023
From: ORIGIN, INC.
To: ORIGIN LIFE SCIENCES, INC.
Reel/Frame 064880/0310 →
CHANGE OF NAME Recorded Mar 17, 2018
From: ADVANCED PLASMA THERAPIES, INC.
To: ORIGIN, INC.
Reel/Frame 045628/0222 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 8, 2018
From: DIMINO, ANDRE'; DRUMMER, MATTHEW; NELSON, HOWARD A., III; PRESTON, MICHAEL D.
To: ADVANCED PLASMA THERAPIES, INC.
Reel/Frame 044873/0134 →
CHANGE OF NAME Recorded Feb 8, 2018
From: ADVANCED PLASMA THERAPIES, INC.
To: ORIGIN, INC.
Reel/Frame 045292/0445 →
Continuity (2)
Provisional Application 62019037 · Jun 30, 2014
Related Publication 20170203115A1 · Jul 20, 2017