Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders
Oral formulations for promoting eye health, and in particular for preventing or treating macular degeneration, are disclosed, containing zeaxanthin, a carotenoid pigment, and at least two or more additional ocular-active nutrients selected from lipoic acid, omega-3 fatty acids, plant-derived compounds such as flavonoids, anthocyanins, or polyphenolics, taurine, carnitine, Coenzyme-Q10, carnosine, and nutrients that stimulate the production of glutathione. Processes are disclosed for identifying ocular-active nutrients that will interact in a synergistic and potentiating manner with zeaxanthin, to provide better and more effective protection, for eye health, than can be provided by zeaxanthin alone. Additional optional agents include zinc, vitamin E, and vitamin C.
1. A nutrient formulation for oral ingestion for a daily dosage comprising:
a. at least 3 milligrams of zeaxanthin that is present in the 3R-3R′ stereoisomer form and is substantially free of meso-zeaxanthin stereoisomers;
b. zinc at a dosage that does not exceed 40 mg of elemental zinc;
c. at least two ocular-active nutrients selected from the group consisting of: (i) at least one tocopherol that provides anti-oxidant activity; (ii) vitamin C; (iii) lipoic acid; (iv) omega-3 fatty acids (EPA and DHA); and (v) coenzyme-Q10;
wherein the nutrient formulation is provided in the form selected from the group consisting of capsules, tablets, liquids, and powders for oral ingestion.
2. The nutrient formulation of claim 1 , further comprising plant-derived active agents.
3. The nutrient formulation of claim 2 , wherein the plant-derived active agents include flavonoids, bioflavonoids, anthocyanins, plant polyphenolics, and phytonutrients.
4. The nutrient formulation of claim 1 , further comprising taurine.
5. The nutrient formulation of claim 1 , further comprising carnitine.
6. The nutrient formulation of claim 1 , further comprising carnosine.
7. The nutrient formulation of claim 1 , further comprising glutathione boosters.
8. The nutrient formulation of claim 1 , wherein the omega-3 fatty acids are derived from fish oil.
9. The nutrient formulation of claim 1 , wherein the nutrient formulation is present in a form that provides sustained release over a span of at least 3 hours following ingestion.
10. The nutrient formulation of claim 1 , wherein the daily dosage of zeaxanthin is at least 10 milligrams.
11. The nutrient formulation of claim 1 , wherein the formulation is in the form of capsules containing oily carrier materials.
12. The nutrient formulation of claim 1 , wherein the at least one tocopherol includes vitamin E.