IP Library Granted Patent US 10,040,769
Granted Patent B2
US 10,040,769 · App. 15/335,971 · Granted Aug 7, 2018

HDAC inhibitors for the treatment of diabetic peripheral neuropathy

Inventors: Olga Golonzhka (Watertown, MA); Matthew B. Jarpe (Quincy, MA)
Assignee: REGENACY PHARMACEUTICALS, LLC
C07D239/42A61K31/164A61K31/337A61K31/495A61K31/505
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Quick Facts
Patent No.
US 10,040,769
App. No.
15/335,971
Granted
Aug 7, 2018
Kind
B2
Abstract

The invention relates to HDAC inhibitors for use in the treatment of diabetic peripheral neuropathy in a subject in need thereof. Also provided herein are methods for treating diabetic peripheral neuropathy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC inhibitor.

Claims (3)

1. A method for treating diabetic peripheral neuropathy in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an HDAC6-specific inhibitor, wherein the HDAC6-specific inhibitor is:

or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , wherein the HDAC6-specific inhibitor is administered by oral administration.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 8, 2020
From: GOLONZHKA, OLGA; JARPE, MATTHEW B.
To: ACETYLON PHARMACEUTICALS, INC.
Reel/Frame 051453/0362 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2018
From: GOLONZHKA, OLGA; JARPE, MATTHEW B.
To: ACETYLON PHARMACEUTICALS, INC.
Reel/Frame 045977/0209 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2018
From: ACETYLON PHARMACEUTICALS, INC.
To: REGENACY PHARMACEUTICALS, LLC
Reel/Frame 045977/0593 →
Continuity (3)
Provisional Application 62246965 · Oct 27, 2015
Provisional Application 62281990 · Jan 22, 2016
Related Publication 20170114023A1 · Apr 27, 2017
Cited By (2)
US 12,201,617 US 12,312,345