IP Library Granted Patent US 10,292,990
Granted Patent B2
US 10,292,990 · App. 15/345,410 · Granted May 21, 2019

Abiraterone steroid formulation

Inventors: Paul Nemeth (Philadelphia, PA); Matt Callahan (Penn Valley, PA); H. William Bosch (Bryn Mawr, PA); Marck Norret (Darlington, AU)
Assignee: SUN PHARMA GLOBAL FZE
A61K31/58A61K9/14A61K31/573A61K45/06
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Quick Facts
Patent No.
US 10,292,990
App. No.
15/345,410
Granted
May 21, 2019
Kind
B2
Abstract

A nanoparticulate composition of abiraterone acetate that allows treatment at a lower dose than convention abiraterone acetate formulations is described as in a method of treating prostate cancer by administering the composition together with a glucocorticoid.

Claims (2)

1. A method of treating prostate cancer comprising administering methylprednisolone and a daily dose of between 400 and 600 mg of abiraterone acetate, wherein the abiraterone acetate is in the form of a tablet or a capsule and has a median particle size of 100 nm to 1000 nm on a volume average basis.

2. The method of claim 1 wherein the daily dose of abiraterone acetate is administered as a single dose.

Assignments (9)
MERGER AND CHANGE OF NAME Recorded Aug 10, 2022
From: SUN PHARMA GLOBAL FZE; SUN PHARMACEUTICAL INDUSTRIES LIMITED
To: SUN PHARMACEUTICAL INDUSTRIES LIMITED
Reel/Frame 060769/0324 →
CORRECTIVE ASSIGNMENT TO CORRECT THE SECOND RECEIVING PARTY REMOVED PREVIOUSLY RECORDED AT REEL: 49387 FRAME: 745. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jul 12, 2019
From: CHURCHILL INTERMEDIATE INC.
To: SUN PHARMA GLOBAL FZE
Reel/Frame 049743/0133 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INFORMATION IN THESUPPORTING ASSIGNMENT DOCUMENT AND THEEXECUTION DATE PREVIOUSLY RECORDED ON REEL 044802 FRAME 0991. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 5, 2019
From: ICEUTICA INC.
To: CHURCHILL INTERMEDIATE INC.
Reel/Frame 049387/0059 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INFORMATION IN THE SUPPORTING ASSIGNMENT AND THE EXECUTION DATE, AND TO REMOVE THE SECOND CONVEYING PARTY NAME AND 8 PROPERTIES PREVIOUSLY RECORDED ON REEL 047137 FRAME 0232. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 5, 2019
From: CHURCHILL INTERMEDIATE INC.
To: SUN PHARMA GLOBAL FZE
Reel/Frame 049387/0745 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 11, 2018
From: CHURCHILL INTERMEDIATE INC.; CHURCHILL PHARMACEUTICALS LLC
To: SUN PHARMA GLOBAL FZE
Reel/Frame 047137/0232 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2018
From: CHURCHILL INTERMEDIATE INC.; CHURCHILL PHARMACEUTICALS LLC
To: SUN PHARMA GLOBAL FZE
Reel/Frame 044829/0325 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 1, 2018
From: ICEUTICA INC.
To: CHURCHILL INTERMEDIATE INC.
Reel/Frame 044802/0991 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2018
From: ICEUTICA INC.
To: CHURCHILL INTERMEDIATE INC.
Reel/Frame 044793/0459 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2017
From: NEMETH, PAUL; CALLAHAN, MATT; BOSCH, H. WILLIAM; NORRET, MARCK
To: ICEUTICA INC.
Reel/Frame 041638/0682 →
Continuity (4)
Continuation 14616625 · Feb 6, 2015
Continuation 14282535 · May 20, 2014
Provisional Application 61883941 · Sep 27, 2013
Related Publication 20170049788A1 · Feb 23, 2017