IP Library Granted Patent US 9,962,361
Granted Patent B2
US 9,962,361 · App. 15/353,260 · Granted May 8, 2018

Isothiocyanate functional surfactants, formulations incorporating the same, and associated methods of use

Inventor: Michael E. Silver (Holland, MI)
Assignee: The William M. Yarbrough Foundation
A61K31/26A61K9/0014A61K9/06A61K31/145A61K31/198A61K45/06A61K47/34C07C331/20
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Quick Facts
Patent No.
US 9,962,361
App. No.
15/353,260
Granted
May 8, 2018
Kind
B2
Abstract

An isothiocyanate functional surfactant, wherein the protonated form of said surfactant is represented by the following chemical structure: wherein X includes an integer ranging from approximately 1 to approximately 25, and wherein Y includes an integer ranging from approximately 6 to approximately 25.

Claims (12)

1. A surfactant formulation, comprising:

a surfactant or a pharmaceutically acceptable salt thereof, wherein the protonated form of said surfactant is represented by the following chemical structure:

wherein R 1 is selected from the group consisting of an alkyl group containing 1 to 25 carbon atom(s); wherein R 2 is selected from the group consisting of NCS; and wherein R 3 -R 5 are each independently selected from the group consisting of H; OH; and an alkyl, and alkanoyl group containing 1 to 25 carbon atom(s) with the proviso that at least one of R 3 -R 5 is selected from the group consisting of an alkyl, and alkanoyl, group containing 8 to 25 carbon atoms; and

a non-hygroscopic solvent.

2. A surfactant formulation, comprising:

a surfactant or a pharmaceutically acceptable salt thereof, wherein the protonated form of said surfactant is represented by the following chemical structure:

wherein X comprises an integer ranging from 1 to 25, and wherein Y comprises an integer ranging from 6 to 25; and

a non-hygroscopic solvent.

3. A surfactant formulation, comprising:

a surfactant or a pharmaceutically acceptable salt thereof to an area affected by phytophotodermatitis, wherein the protonated form of said surfactant is represented by the following chemical structure:

and

a non-hygroscopic solvent.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2016
From: SILVER, MICHAEL E.
To: THE WILLIAM M. YARBROUGH FOUNDATION
Reel/Frame 040346/0255 →
Continuity (6)
Continuation In Part 15297304 · Oct 19, 2016
Continuation 14594788 · Jan 12, 2015
Continuation 13342516 · Jan 3, 2012
Provisional Application 61502067 · Jun 28, 2011
Provisional Application 61429325 · Jan 3, 2011
Related Publication 20170065548A1 · Mar 9, 2017